Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis

Species-specific recombinant proteins of leptospira are genetically engineered by the method of gene manipulation. Their high activity and antigenic specificity are established. On the basis of these proteins an immunoassay test kit for detecting JgG to Leptospira is constructed.

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Main Authors: V. N. Kulikov, A. A. Kozarenco, N. K. Tokarevich, N. A. Stoyanova
Format: Article
Language:Russian
Published: Numikom LLC 2015-04-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/29
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author V. N. Kulikov
A. A. Kozarenco
N. K. Tokarevich
N. A. Stoyanova
author_facet V. N. Kulikov
A. A. Kozarenco
N. K. Tokarevich
N. A. Stoyanova
author_sort V. N. Kulikov
collection DOAJ
description Species-specific recombinant proteins of leptospira are genetically engineered by the method of gene manipulation. Their high activity and antigenic specificity are established. On the basis of these proteins an immunoassay test kit for detecting JgG to Leptospira is constructed.
format Article
id doaj-art-f6d2255cd2a3408e8f6e3c73cf0c9d9b
institution DOAJ
issn 2073-3046
2619-0494
language Russian
publishDate 2015-04-01
publisher Numikom LLC
record_format Article
series Эпидемиология и вакцинопрофилактика
spelling doaj-art-f6d2255cd2a3408e8f6e3c73cf0c9d9b2025-08-20T03:21:22ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942015-04-01142101210.31631/2073-3046-2015-14-2-10-1228Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of LeptospirosisV. N. Kulikov0A. A. Kozarenco1N. K. Tokarevich2N. A. Stoyanova3Limited Liability Company«Omnix»Limited Liability Company«Omnix»Saint-Petersburg Pasteur InstituteSaint-Petersburg Pasteur InstituteSpecies-specific recombinant proteins of leptospira are genetically engineered by the method of gene manipulation. Their high activity and antigenic specificity are established. On the basis of these proteins an immunoassay test kit for detecting JgG to Leptospira is constructed.https://www.epidemvac.ru/jour/article/view/29лептоспироздиагностикаleptospirosisdiagnostics
spellingShingle V. N. Kulikov
A. A. Kozarenco
N. K. Tokarevich
N. A. Stoyanova
Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
Эпидемиология и вакцинопрофилактика
лептоспироз
диагностика
leptospirosis
diagnostics
title Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
title_full Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
title_fullStr Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
title_full_unstemmed Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
title_short Development of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
title_sort development of recombinant leptospira antigenes for the purpose of creation of immunoassay test kit for diagnosis of leptospirosis
topic лептоспироз
диагностика
leptospirosis
diagnostics
url https://www.epidemvac.ru/jour/article/view/29
work_keys_str_mv AT vnkulikov developmentofrecombinantleptospiraantigenesforthepurposeofcreationofimmunoassaytestkitfordiagnosisofleptospirosis
AT aakozarenco developmentofrecombinantleptospiraantigenesforthepurposeofcreationofimmunoassaytestkitfordiagnosisofleptospirosis
AT nktokarevich developmentofrecombinantleptospiraantigenesforthepurposeofcreationofimmunoassaytestkitfordiagnosisofleptospirosis
AT nastoyanova developmentofrecombinantleptospiraantigenesforthepurposeofcreationofimmunoassaytestkitfordiagnosisofleptospirosis