Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study.
<h4>Background</h4>Multimorbidity is associated with poor quality of life, polypharmacy, health care costs and mortality, with those affected potentially benefitting from a healthy lifestyle. We assessed a comprehensive set of lifestyle factors in relation to multimorbidity with major ch...
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0287263 |
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| author | Jacobien Niebuur Judith M Vonk Yihui Du Geertruida H de Bock Gerton Lunter Paul F M Krabbe Behrooz Z Alizadeh Harold Snieder Nynke Smidt Marike Boezen Eva Corpeleijn |
| author_facet | Jacobien Niebuur Judith M Vonk Yihui Du Geertruida H de Bock Gerton Lunter Paul F M Krabbe Behrooz Z Alizadeh Harold Snieder Nynke Smidt Marike Boezen Eva Corpeleijn |
| author_sort | Jacobien Niebuur |
| collection | DOAJ |
| description | <h4>Background</h4>Multimorbidity is associated with poor quality of life, polypharmacy, health care costs and mortality, with those affected potentially benefitting from a healthy lifestyle. We assessed a comprehensive set of lifestyle factors in relation to multimorbidity with major chronic diseases.<h4>Methods</h4>This cross-sectional study utilised baseline data for adults from the prospective Lifelines Cohort in the north of the Netherlands (N = 79,345). We defined multimorbidity as the co-existence of two or more chronic diseases (i.e. cardiovascular disease, cancer, respiratory disease, type 2 diabetes) and evaluated factors in six lifestyle domains (nutrition, physical (in)activity, substance abuse, sleep, stress, relationships) among groups by the number of chronic diseases (≥2, 1, 0). Multinomial logistic regression models were created, adjusted for appropriate confounders, and odds ratios (OR) with 95% confidence intervals (95%CI) were reported.<h4>Results</h4>3,712 participants had multimorbidity (4.7%, age 53.5 ± 12.5 years), and this group tended to have less healthy lifestyles. Compared to those without chronic diseases, those with multimorbidity reported physical inactivity more often (OR, 1.15; 95%CI, 1.06-1.25; not significant for one condition), chronic stress (OR, 2.14; 95%CI, 1.92-2.38) and inadequate sleep (OR, 1.70; 95%CI, 1.41-2.06); as expected, they more often watched television (OR, 1.70; 95%CI, 1.42-2.04) and currently smoked (OR, 1.91; 95%CI, 1.73-2.11), but they also had lower alcohol intakes (OR, 0.66; 95%CI, 0.59-0.74).<h4>Conclusions</h4>Chronic stress and poor sleep, in addition to physical inactivity and smoking, are lifestyle factors of great concern in patients with multimorbidity. |
| format | Article |
| id | doaj-art-f6cd1cec76864fb0a8cb7fcf91eeec22 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj-art-f6cd1cec76864fb0a8cb7fcf91eeec222025-08-20T03:22:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01187e028726310.1371/journal.pone.0287263Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study.Jacobien NiebuurJudith M VonkYihui DuGeertruida H de BockGerton LunterPaul F M KrabbeBehrooz Z AlizadehHarold SniederNynke SmidtMarike BoezenEva Corpeleijn<h4>Background</h4>Multimorbidity is associated with poor quality of life, polypharmacy, health care costs and mortality, with those affected potentially benefitting from a healthy lifestyle. We assessed a comprehensive set of lifestyle factors in relation to multimorbidity with major chronic diseases.<h4>Methods</h4>This cross-sectional study utilised baseline data for adults from the prospective Lifelines Cohort in the north of the Netherlands (N = 79,345). We defined multimorbidity as the co-existence of two or more chronic diseases (i.e. cardiovascular disease, cancer, respiratory disease, type 2 diabetes) and evaluated factors in six lifestyle domains (nutrition, physical (in)activity, substance abuse, sleep, stress, relationships) among groups by the number of chronic diseases (≥2, 1, 0). Multinomial logistic regression models were created, adjusted for appropriate confounders, and odds ratios (OR) with 95% confidence intervals (95%CI) were reported.<h4>Results</h4>3,712 participants had multimorbidity (4.7%, age 53.5 ± 12.5 years), and this group tended to have less healthy lifestyles. Compared to those without chronic diseases, those with multimorbidity reported physical inactivity more often (OR, 1.15; 95%CI, 1.06-1.25; not significant for one condition), chronic stress (OR, 2.14; 95%CI, 1.92-2.38) and inadequate sleep (OR, 1.70; 95%CI, 1.41-2.06); as expected, they more often watched television (OR, 1.70; 95%CI, 1.42-2.04) and currently smoked (OR, 1.91; 95%CI, 1.73-2.11), but they also had lower alcohol intakes (OR, 0.66; 95%CI, 0.59-0.74).<h4>Conclusions</h4>Chronic stress and poor sleep, in addition to physical inactivity and smoking, are lifestyle factors of great concern in patients with multimorbidity.https://doi.org/10.1371/journal.pone.0287263 |
| spellingShingle | Jacobien Niebuur Judith M Vonk Yihui Du Geertruida H de Bock Gerton Lunter Paul F M Krabbe Behrooz Z Alizadeh Harold Snieder Nynke Smidt Marike Boezen Eva Corpeleijn Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. PLoS ONE |
| title | Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. |
| title_full | Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. |
| title_fullStr | Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. |
| title_full_unstemmed | Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. |
| title_short | Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. |
| title_sort | lifestyle factors related to prevalent chronic disease multimorbidity a population based cross sectional study |
| url | https://doi.org/10.1371/journal.pone.0287263 |
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