PD-1 and LAG-3 were optimal combination of immune checkpoints for predicting poor clinical outcomes of patients with ovarian cancer

PD-1 and LAG-3 were optimal combination of immune checkpoints for predicting poor clinical outcomes of patients with ovarian cancer

BackgroundAlthough immune checkpoint blockade (ICB) therapy has transformed the therapeutic landscape for ovarian cancer (OC), the predictive utility of immune checkpoint (IC) expression signatures in stratifying clinical outcomes requires further systematic interrogation.MethodsTranscriptomic profi...

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Bibliographic Details
Main Authors: Yifan Wu, Cunte Chen, Yingwen Cui, Ruoyao Zou, Yaoxiang Yang, Fengjie Sun, Yanzi Du, Peipei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint
PD-1
LAG-3
prognosis
ovarian cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1656242/full
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