Correlation of serum Insulin-Like Growth Factor one with acne severity
Background and Objectives: Acne is a common chronic inflammatory skin condition; Acne could present as inflammatory or non-inflammatory lesion. Acne can be varied in severity from patient to another, generally, it can present in mild, moderate or severe degree. Excessive production of sebum by s...
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Kurdistan Higher Council Of Medical Specialties
2022-07-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/52 |
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| author | Saedi Khaleel Fattah Ali Mozan Dhahir Elethawi |
| author_facet | Saedi Khaleel Fattah Ali Mozan Dhahir Elethawi |
| author_sort | Saedi Khaleel Fattah |
| collection | DOAJ |
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Background and Objectives: Acne is a common chronic inflammatory skin condition; Acne could present as inflammatory or non-inflammatory lesion. Acne can be varied in severity from patient to another, generally, it can present in mild, moderate or severe degree.
Excessive production of sebum by sebaceous glands in the skin contributes in acne formation. One of the factors associated with the production of sebum is Insulin-Like Growth Factor in serum. Current study tries to find any association between acne severity and serum Insulin-Like Growth Factor.
Method: On a sample of 40 female patients with acne, aged 14-26 years at the outpatient clinic as a cross sectional study. Serum IGF-1 level was compared to their acne severity across three groups, mild, moderate and severe acne. Global acne grading system was used to classify the acne severity.
Results: Median levels of IGF-1 were 208.09 ng/ml. Mean serum level of IGF-1 is 254.53ng/ml, 200.03ng/ml and 172.39ng/ml in severe, moderate and mild acne respectively. Acne severity strongly associated with serum level of IGF-1 which is statistically significant. No significantly association between serum level of Insulin-Like Growth Factor and the age of patients was found. Likewise, the severity degree of acne has no association with body mass index
Conclusion: There is a direct relationship between mean level of IGF-1 in patients with AV with degree of their acne severity
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| format | Article |
| id | doaj-art-f643d492ed414e88b83bc5eeee2ef3a3 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-f643d492ed414e88b83bc5eeee2ef3a32025-08-20T02:11:47ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802022-07-017110.56056/amj.2022.16552Correlation of serum Insulin-Like Growth Factor one with acne severitySaedi Khaleel Fattah0Ali Mozan Dhahir Elethawi1KBMS-Dermatology trainee, Sulaimani center for treatment of skin diseasesM.B.Ch.B., FICMS, CABD. Assist. Professor of dermatology, College of Medicine, University of Sulaimani Background and Objectives: Acne is a common chronic inflammatory skin condition; Acne could present as inflammatory or non-inflammatory lesion. Acne can be varied in severity from patient to another, generally, it can present in mild, moderate or severe degree. Excessive production of sebum by sebaceous glands in the skin contributes in acne formation. One of the factors associated with the production of sebum is Insulin-Like Growth Factor in serum. Current study tries to find any association between acne severity and serum Insulin-Like Growth Factor. Method: On a sample of 40 female patients with acne, aged 14-26 years at the outpatient clinic as a cross sectional study. Serum IGF-1 level was compared to their acne severity across three groups, mild, moderate and severe acne. Global acne grading system was used to classify the acne severity. Results: Median levels of IGF-1 were 208.09 ng/ml. Mean serum level of IGF-1 is 254.53ng/ml, 200.03ng/ml and 172.39ng/ml in severe, moderate and mild acne respectively. Acne severity strongly associated with serum level of IGF-1 which is statistically significant. No significantly association between serum level of Insulin-Like Growth Factor and the age of patients was found. Likewise, the severity degree of acne has no association with body mass index Conclusion: There is a direct relationship between mean level of IGF-1 in patients with AV with degree of their acne severity https://amj.khcms.edu.krd/index.php/main/article/view/52Insulin growth factor-1Acne vulgaris'Acne severity |
| spellingShingle | Saedi Khaleel Fattah Ali Mozan Dhahir Elethawi Correlation of serum Insulin-Like Growth Factor one with acne severity Advanced Medical Journal Insulin growth factor-1 Acne vulgaris ' Acne severity |
| title | Correlation of serum Insulin-Like Growth Factor one with acne severity |
| title_full | Correlation of serum Insulin-Like Growth Factor one with acne severity |
| title_fullStr | Correlation of serum Insulin-Like Growth Factor one with acne severity |
| title_full_unstemmed | Correlation of serum Insulin-Like Growth Factor one with acne severity |
| title_short | Correlation of serum Insulin-Like Growth Factor one with acne severity |
| title_sort | correlation of serum insulin like growth factor one with acne severity |
| topic | Insulin growth factor-1 Acne vulgaris ' Acne severity |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/52 |
| work_keys_str_mv | AT saedikhaleelfattah correlationofseruminsulinlikegrowthfactoronewithacneseverity AT alimozandhahirelethawi correlationofseruminsulinlikegrowthfactoronewithacneseverity |