Age-Dependent DNA Methylation Variability on the X-Chromosome in Male and Female Twins

We aimed to explore the age-dependent epigenetic variability on the X-chromosome with consideration of X-chromosome inactivation by applying a sex-stratified regression analysis to DNA methylation array data on X-linked CpGs in aging identical twins. We found 13 X-linked CpGs showing age-related sig...

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Bibliographic Details
Main Authors: Qihua Tan, Hikmat Alo, Marianne Nygaard, Mette Sørensen, Alisa Saleh, Jonas Mengel-From, Kaare Christensen
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Epigenomes
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Online Access:https://www.mdpi.com/2075-4655/8/4/43
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