Imatinib Mesylate Alters the Expression of Genes Related to Disease Progression in an Animal Model of Uveal Melanoma

Imatinib mesylate (IM) is a compound that inhibits both BCR-ABL tyrosine kinase and c-kit receptors. Tyrosine kinases are important in cellular signaling and mediate major cellular processes such as proliferation, differentiation, apoptosis, attachment, and migration. Twenty-six albino rabbits were...

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Bibliographic Details
Main Authors: Bruno F. Fernandes, Sebastian Di Cesare, Rubens Neto Belfort, Shawn Maloney, Claudia Martins, Enzo Castiglione, Jordan Isenberg, Daniel Abourbih, Emilia Antecka, Miguel N. Burnier Jr.
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0010
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