Environmental risk factors, protective factors, and biomarkers for amyotrophic lateral sclerosis: an umbrella review

IntroductionAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the rapid loss of motor neurons. Given the significant global economic impact of ALS, effective preventive measures are urgently needed to reduce the incidence of this devastating disease. Recent me...

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Main Authors: Qian Wu, Junyi Yang, Yuanjie Duan, Yumei Ma, Yue Zhang, Shutong Tan, Jinke Wang, Yaxin Wang, Binhui Liu, Jian Zhang, Xu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1541779/full
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