Impact of Dietary Factors on Thyroid Function and Disorders

Thyroid health is intricately linked to nutritional status, as multiple micronutrients and dietary components modulate hormone biosynthesis, metabolism, and immune function. The increasing global prevalence of autoimmune thyroid disorders, particularly Hashimoto’s thyroiditis and Graves’ disease, u...

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Main Authors: Maksymilian Czarnota, Maria Wojcieszek, Dominika Gacka, Aleksandra Żołnierek, Katarzyna Gondek, Magdalena Fidelis, Aleksandra Mączyńska, Wiktoria Szumlińska, Noor Al-karawi, Paulina Kędziorek, Zuzanna Tanç
Format: Article
Language:English
Published: Kazimierz Wielki University 2025-06-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/60580
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author Maksymilian Czarnota
Maria Wojcieszek
Dominika Gacka
Aleksandra Żołnierek
Katarzyna Gondek
Magdalena Fidelis
Aleksandra Mączyńska
Wiktoria Szumlińska
Noor Al-karawi
Paulina Kędziorek
Zuzanna Tanç
author_facet Maksymilian Czarnota
Maria Wojcieszek
Dominika Gacka
Aleksandra Żołnierek
Katarzyna Gondek
Magdalena Fidelis
Aleksandra Mączyńska
Wiktoria Szumlińska
Noor Al-karawi
Paulina Kędziorek
Zuzanna Tanç
author_sort Maksymilian Czarnota
collection DOAJ
description Thyroid health is intricately linked to nutritional status, as multiple micronutrients and dietary components modulate hormone biosynthesis, metabolism, and immune function. The increasing global prevalence of autoimmune thyroid disorders, particularly Hashimoto’s thyroiditis and Graves’ disease, underscores the need to examine the influence of modifiable dietary factors on thyroid pathophysiology. This narrative review aimed to evaluate current evidence on the role of nutrition—especially micronutrients such as iodine, selenium, iron, zinc, and vitamin D—in thyroid function and autoimmunity. A structured literature search was conducted using PubMed and Scopus to identify relevant human studies published between January 2002 and March 2025. A total of forty-one peer-reviewed articles were selected based on predefined inclusion criteria and assessed for scientific rigor and relevance. The evidence confirms the critical involvement of iodine and selenium in thyroid hormone synthesis and immune modulation, while iron and zinc were found to support enzymatic activity and endocrine stability. Vitamin D emerged as a potential immunoregulatory agent in autoimmune thyroid disease. Furthermore, certain macronutrients—including high-quality proteins, fiber, and omega-3 fatty acids—as well as dietary patterns such as the Mediterranean diet, were associated with favorable thyroid outcomes. Conversely, the intake of goitrogenic foods and soy isoflavones may necessitate caution in predisposed individuals. These findings highlight the relevance of individualized, evidence-based nutritional strategies as adjunctive approaches in the prevention and clinical management of thyroid disorders.
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spelling doaj-art-f6203d5e5fa4477795fdc28ff983e8832025-08-20T02:42:12ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-06-018210.12775/JEHS.2025.82.60580Impact of Dietary Factors on Thyroid Function and DisordersMaksymilian Czarnota0https://orcid.org/0009-0002-9322-4494Maria Wojcieszek1https://orcid.org/0009-0008-3807-7317Dominika Gacka2https://orcid.org/0009-0006-7444-0326Aleksandra Żołnierek3https://orcid.org/0009-0000-0396-4479Katarzyna Gondek4https://orcid.org/0009-0001-2833-8287Magdalena Fidelis5https://orcid.org/0009-0001-7356-8065Aleksandra Mączyńska6https://orcid.org/0009-0006-6887-8188Wiktoria Szumlińska7https://orcid.org/0009-0001-5286-4228Noor Al-karawi8https://orcid.org/0009-0005-6647-1520Paulina Kędziorek9https://orcid.org/0009-0002-8126-5803Zuzanna Tanç10https://orcid.org/0009-0009-3030-7592Szpital Morski im. PCK w GdyniMedical University of Warsaw, Żwirki i Wigury 61, 02-091 Warsaw, PolandSzpital Morski im. PCK, ul. Powstania Styczniowego 1, 81-519 Gdynia, PolandSpecjalistyczna Przychodnia Lekarska dla Pracowników Wojska SPZOZ w Warszawie, Nowowiejska 31, 00-665 Warszawa, PolandPIM MSWiA w Warszawie, ul.Wołoska 137, 02-507 Warszawa, PolandSzpital Morski im. PCK, ul. Powstania Styczniowego 1, 81-519 Gdynia, PolandLUX MED Sp. z o.o., ul. Szturmowa 2, 02-678 WarszawaPIM MSWiA w Warszawie, ul.Wołoska 137, 02-507 Warszawa, PolandPIM MSWiA w Warszawie, ul.Wołoska 137, 02-507 Warszawa, PolandSPZOZ - ZZ im. Duńskiego Czerwonego Krzyża, ul. Wincentego Witosa 2, 06-200 Maków MazowieckiSPZOZ - ZZ im. Duńskiego Czerwonego Krzyża, ul. Wincentego Witosa 2, 06-200 Maków Mazowiecki Thyroid health is intricately linked to nutritional status, as multiple micronutrients and dietary components modulate hormone biosynthesis, metabolism, and immune function. The increasing global prevalence of autoimmune thyroid disorders, particularly Hashimoto’s thyroiditis and Graves’ disease, underscores the need to examine the influence of modifiable dietary factors on thyroid pathophysiology. This narrative review aimed to evaluate current evidence on the role of nutrition—especially micronutrients such as iodine, selenium, iron, zinc, and vitamin D—in thyroid function and autoimmunity. A structured literature search was conducted using PubMed and Scopus to identify relevant human studies published between January 2002 and March 2025. A total of forty-one peer-reviewed articles were selected based on predefined inclusion criteria and assessed for scientific rigor and relevance. The evidence confirms the critical involvement of iodine and selenium in thyroid hormone synthesis and immune modulation, while iron and zinc were found to support enzymatic activity and endocrine stability. Vitamin D emerged as a potential immunoregulatory agent in autoimmune thyroid disease. Furthermore, certain macronutrients—including high-quality proteins, fiber, and omega-3 fatty acids—as well as dietary patterns such as the Mediterranean diet, were associated with favorable thyroid outcomes. Conversely, the intake of goitrogenic foods and soy isoflavones may necessitate caution in predisposed individuals. These findings highlight the relevance of individualized, evidence-based nutritional strategies as adjunctive approaches in the prevention and clinical management of thyroid disorders. https://apcz.umk.pl/JEHS/article/view/60580Thyroid functionAutoimmune thyroid diseaseNutritional factorsMicronutrientsDietary supplementationHashimoto’s thyroiditis
spellingShingle Maksymilian Czarnota
Maria Wojcieszek
Dominika Gacka
Aleksandra Żołnierek
Katarzyna Gondek
Magdalena Fidelis
Aleksandra Mączyńska
Wiktoria Szumlińska
Noor Al-karawi
Paulina Kędziorek
Zuzanna Tanç
Impact of Dietary Factors on Thyroid Function and Disorders
Journal of Education, Health and Sport
Thyroid function
Autoimmune thyroid disease
Nutritional factors
Micronutrients
Dietary supplementation
Hashimoto’s thyroiditis
title Impact of Dietary Factors on Thyroid Function and Disorders
title_full Impact of Dietary Factors on Thyroid Function and Disorders
title_fullStr Impact of Dietary Factors on Thyroid Function and Disorders
title_full_unstemmed Impact of Dietary Factors on Thyroid Function and Disorders
title_short Impact of Dietary Factors on Thyroid Function and Disorders
title_sort impact of dietary factors on thyroid function and disorders
topic Thyroid function
Autoimmune thyroid disease
Nutritional factors
Micronutrients
Dietary supplementation
Hashimoto’s thyroiditis
url https://apcz.umk.pl/JEHS/article/view/60580
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