A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx

Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma wi...

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Main Authors: Harry Boamah, Billy Ballard
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/370204
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author Harry Boamah
Billy Ballard
author_facet Harry Boamah
Billy Ballard
author_sort Harry Boamah
collection DOAJ
description Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.
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spelling doaj-art-f61ef7377b87461595828b54af8281472025-02-03T01:11:47ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/370204370204A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the LarynxHarry Boamah0Billy Ballard1Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USADepartment of Pathology, Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USASpindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.http://dx.doi.org/10.1155/2012/370204
spellingShingle Harry Boamah
Billy Ballard
A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
Case Reports in Medicine
title A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
title_full A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
title_fullStr A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
title_full_unstemmed A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
title_short A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx
title_sort case report of spindle cell sarcomatoid carcinoma of the larynx
url http://dx.doi.org/10.1155/2012/370204
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