Epidermolysis bullosa
Epidermolysis bullosa (EB) is a hereditary multisystemic disease caused by genetic defects in the skin's structural proteins. Depending on the type of disease, symptoms vary from localised fragility and bullae to a widespread generalised form, including extracutaneous manifestations. In the mos...
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| Format: | Article |
| Language: | English |
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City Medical emergency department, Belgrade
2024-01-01
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| Series: | Halo 194 |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/2334-6477/2024/2334-64772402061A.pdf |
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| author | Anđelić Slađana Stefanović Ivana Tasić-Uroš Danijela Milivojčević- Bevc Ivana Savić Nikola |
| author_facet | Anđelić Slađana Stefanović Ivana Tasić-Uroš Danijela Milivojčević- Bevc Ivana Savić Nikola |
| author_sort | Anđelić Slađana |
| collection | DOAJ |
| description | Epidermolysis bullosa (EB) is a hereditary multisystemic disease caused by genetic defects in the skin's structural proteins. Depending on the type of disease, symptoms vary from localised fragility and bullae to a widespread generalised form, including extracutaneous manifestations. In the most severe forms, EB causes death in the earliest period of life. The treatment of EB is complex and usually requires the involvement of several different specialists. Without curative therapy, treatment is oriented towards supportive care, symptom control, and preventing mild to severe complications. Vector gene therapy Vyjuvek (beremagene geperpavec), based on the herpes simplex virus type 1, is a new hope for treating wounds in patients older than six months who suffer from dystrophic forms of EB. |
| format | Article |
| id | doaj-art-f60c63c102aa4129ac6b475a347d6c62 |
| institution | Kabale University |
| issn | 2334-6477 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | City Medical emergency department, Belgrade |
| record_format | Article |
| series | Halo 194 |
| spelling | doaj-art-f60c63c102aa4129ac6b475a347d6c622025-02-05T13:08:55ZengCity Medical emergency department, BelgradeHalo 1942334-64772024-01-01302617010.5937/halo30-519032334-64772402061AEpidermolysis bullosaAnđelić Slađana0https://orcid.org/0000-0002-5233-8287Stefanović Ivana1https://orcid.org/0009-0004-4064-3577Tasić-Uroš Danijela2https://orcid.org/0009-0006-5419-9758Milivojčević- Bevc Ivana3https://orcid.org/0009-0007-1346-126XSavić Nikola4https://orcid.org/0000-0002-6687-9455Zavod za urgentnu medicinu, Beograd, SerbiaZavod za urgentnu medicinu, Beograd, SerbiaZavod za urgentnu medicinu, Beograd, SerbiaZavod za urgentnu medicinu, Beograd, SerbiaUniverzitet Singidunum, Fakultet zdravstvenih i poslovnih studija, Valjevo, SerbiaEpidermolysis bullosa (EB) is a hereditary multisystemic disease caused by genetic defects in the skin's structural proteins. Depending on the type of disease, symptoms vary from localised fragility and bullae to a widespread generalised form, including extracutaneous manifestations. In the most severe forms, EB causes death in the earliest period of life. The treatment of EB is complex and usually requires the involvement of several different specialists. Without curative therapy, treatment is oriented towards supportive care, symptom control, and preventing mild to severe complications. Vector gene therapy Vyjuvek (beremagene geperpavec), based on the herpes simplex virus type 1, is a new hope for treating wounds in patients older than six months who suffer from dystrophic forms of EB.https://scindeks-clanci.ceon.rs/data/pdf/2334-6477/2024/2334-64772402061A.pdfepidermolysis bullosaclinical presentationtherapytreatmentvyuvek |
| spellingShingle | Anđelić Slađana Stefanović Ivana Tasić-Uroš Danijela Milivojčević- Bevc Ivana Savić Nikola Epidermolysis bullosa Halo 194 epidermolysis bullosa clinical presentation therapy treatment vyuvek |
| title | Epidermolysis bullosa |
| title_full | Epidermolysis bullosa |
| title_fullStr | Epidermolysis bullosa |
| title_full_unstemmed | Epidermolysis bullosa |
| title_short | Epidermolysis bullosa |
| title_sort | epidermolysis bullosa |
| topic | epidermolysis bullosa clinical presentation therapy treatment vyuvek |
| url | https://scindeks-clanci.ceon.rs/data/pdf/2334-6477/2024/2334-64772402061A.pdf |
| work_keys_str_mv | AT anđelicslađana epidermolysisbullosa AT stefanovicivana epidermolysisbullosa AT tasicurosdanijela epidermolysisbullosa AT milivojcevicbevcivana epidermolysisbullosa AT savicnikola epidermolysisbullosa |