Cephalexin Induced Cholestatic Jaundice
Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including el...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/260743 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568047731212288 |
|---|---|
| author | Abhinav Agrawal Mana Rao Sarfaraz Jasdanwala Ajay Mathur Margaret Eng |
| author_facet | Abhinav Agrawal Mana Rao Sarfaraz Jasdanwala Ajay Mathur Margaret Eng |
| author_sort | Abhinav Agrawal |
| collection | DOAJ |
| description | Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment. |
| format | Article |
| id | doaj-art-f5f70bef5f834cb8a28596c35a6d40a5 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-f5f70bef5f834cb8a28596c35a6d40a52025-02-03T00:59:56ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362014-01-01201410.1155/2014/260743260743Cephalexin Induced Cholestatic JaundiceAbhinav Agrawal0Mana Rao1Sarfaraz Jasdanwala2Ajay Mathur3Margaret Eng4Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USADepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USADepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USASection of Infectious Diseases, Monmouth Medical Center, Long Branch, NJ 07740, USADepartment of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USACephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment.http://dx.doi.org/10.1155/2014/260743 |
| spellingShingle | Abhinav Agrawal Mana Rao Sarfaraz Jasdanwala Ajay Mathur Margaret Eng Cephalexin Induced Cholestatic Jaundice Case Reports in Gastrointestinal Medicine |
| title | Cephalexin Induced Cholestatic Jaundice |
| title_full | Cephalexin Induced Cholestatic Jaundice |
| title_fullStr | Cephalexin Induced Cholestatic Jaundice |
| title_full_unstemmed | Cephalexin Induced Cholestatic Jaundice |
| title_short | Cephalexin Induced Cholestatic Jaundice |
| title_sort | cephalexin induced cholestatic jaundice |
| url | http://dx.doi.org/10.1155/2014/260743 |
| work_keys_str_mv | AT abhinavagrawal cephalexininducedcholestaticjaundice AT manarao cephalexininducedcholestaticjaundice AT sarfarazjasdanwala cephalexininducedcholestaticjaundice AT ajaymathur cephalexininducedcholestaticjaundice AT margareteng cephalexininducedcholestaticjaundice |