The Protective Effects of Metformin and Vitamin C and Their Co-Administration in Bleomycin-Induced Pulmonary Fibrosis in Mice

Bleomycin, an antibacterial antibiotic, is used in chemotherapy and is effective against various forms of human carcinomas. However, its use is limited due to its tendency to cause pulmonary fibrosis. Oxidative stress and excessive expression of TGF beta occur in pulmonary fibrosis, leading to cellu...

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Bibliographic Details
Main Authors: Mohammad Ebrahim Abbaszadeh, Mohammad Rafi Khezri, Morteza Ghasemnejad-Berenji
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advances in Pharmacological and Pharmaceutical Sciences
Online Access:http://dx.doi.org/10.1155/adpp/5227142
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