Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria

Abstract To ensure the prevention of mother-to-child-transmission of HIV (MTCT), 81% of pregnant women received antiretroviral therapy (ART) in 2021 worldwide. Despite the global efforts to prevent MTCT of HIV, significant knowledge gaps persist among these women including a lack of basic knowledge...

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Main Authors: Oludare ‘Sunbo Adewuyi, Joseph Yaria, James Aigboje Orevba, Patrick Nguku, Magbagbeola David Dairo
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-92745-8
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author Oludare ‘Sunbo Adewuyi
Joseph Yaria
James Aigboje Orevba
Patrick Nguku
Magbagbeola David Dairo
author_facet Oludare ‘Sunbo Adewuyi
Joseph Yaria
James Aigboje Orevba
Patrick Nguku
Magbagbeola David Dairo
author_sort Oludare ‘Sunbo Adewuyi
collection DOAJ
description Abstract To ensure the prevention of mother-to-child-transmission of HIV (MTCT), 81% of pregnant women received antiretroviral therapy (ART) in 2021 worldwide. Despite the global efforts to prevent MTCT of HIV, significant knowledge gaps persist among these women including a lack of basic knowledge of HIV and ART. This study aimed to determine the levels of HIV knowledge, knowledge of ART, and attitude toward ART in HIV-positive pregnant women in Kaduna State. It was a hospital-based, cross-sectional study among 318 HIV-positive pregnant women attending antenatal care in the nine selected hospitals using a three-stage sampling technique. Data was collected using the Open Data Kit. Up to 54.4% had a fair knowledge of ART while 75.4% of the respondents had good knowledge of HIV, and up to 98.6% had a positive attitude towards ART. Knowledge of ART and attitude to ART are positively influenced by receiving multiple counselling (p = 0.031, aOR = 6), being on ART for ≥ 2 years (p = 0.021, aOR = 6); and not taking unprescribed medications (p = 0.047, aOR = 17) respectively. Sustained, focused counselling and patient education are necessary to establish and optimise the required adherence in this group. Also, implement clear task-sharing strategies for health personnel to provide tailored services.
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spelling doaj-art-f5e4a2e7ee9f4a03ab16e143a6a01a132025-08-20T03:07:41ZengNature PortfolioScientific Reports2045-23222025-04-0115111010.1038/s41598-025-92745-8Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, NigeriaOludare ‘Sunbo Adewuyi0Joseph Yaria1James Aigboje Orevba2Patrick Nguku3Magbagbeola David Dairo4Nigeria Centre for Disease Control and PreventionMedicine Department, College of Medicine, University of IbadanAfrica Field Epidemiology NetworkNigeria Field Epidemiology Laboratory Training ProgrammeNigeria Field Epidemiology Laboratory Training ProgrammeAbstract To ensure the prevention of mother-to-child-transmission of HIV (MTCT), 81% of pregnant women received antiretroviral therapy (ART) in 2021 worldwide. Despite the global efforts to prevent MTCT of HIV, significant knowledge gaps persist among these women including a lack of basic knowledge of HIV and ART. This study aimed to determine the levels of HIV knowledge, knowledge of ART, and attitude toward ART in HIV-positive pregnant women in Kaduna State. It was a hospital-based, cross-sectional study among 318 HIV-positive pregnant women attending antenatal care in the nine selected hospitals using a three-stage sampling technique. Data was collected using the Open Data Kit. Up to 54.4% had a fair knowledge of ART while 75.4% of the respondents had good knowledge of HIV, and up to 98.6% had a positive attitude towards ART. Knowledge of ART and attitude to ART are positively influenced by receiving multiple counselling (p = 0.031, aOR = 6), being on ART for ≥ 2 years (p = 0.021, aOR = 6); and not taking unprescribed medications (p = 0.047, aOR = 17) respectively. Sustained, focused counselling and patient education are necessary to establish and optimise the required adherence in this group. Also, implement clear task-sharing strategies for health personnel to provide tailored services.https://doi.org/10.1038/s41598-025-92745-8ART knowledgeHIVPregnant womenPMTCTAttitude to ART
spellingShingle Oludare ‘Sunbo Adewuyi
Joseph Yaria
James Aigboje Orevba
Patrick Nguku
Magbagbeola David Dairo
Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
Scientific Reports
ART knowledge
HIV
Pregnant women
PMTCT
Attitude to ART
title Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
title_full Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
title_fullStr Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
title_full_unstemmed Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
title_short Beyond HAART: unveiling the reality of antiretroviral therapy knowledge among pregnant women living with HIV in Kaduna State, Nigeria
title_sort beyond haart unveiling the reality of antiretroviral therapy knowledge among pregnant women living with hiv in kaduna state nigeria
topic ART knowledge
HIV
Pregnant women
PMTCT
Attitude to ART
url https://doi.org/10.1038/s41598-025-92745-8
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