Better treatment outcomes with aripiprazole long-acting injection in community and incarcerated patients with serious mental illness

Better treatment outcomes with aripiprazole long-acting injection in community and incarcerated patients with serious mental illness

ImportanceAripiprazole, a partial D2 receptor agonist, is proposed to enhance prefrontal cortex (PFC) dopamine function, improving working memory and GABA transmission, which supports social functioning. Long-acting injectable (LAI) antipsychotics are known to improve patient adherence, leading to e...

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Bibliographic Details
Main Authors: Erasmia I. Koiliari, Ioannis Mouzas, Georgios Alevizopoulos, Otto Lesch, Henriette Walter, Emmanouil L. Pasparakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Psychiatry
Subjects:
aripiprazole
long -acting treatment
serious mental illness (SMI)
psychosis
quality of life
hospitalizations
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1499400/full
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