Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease

BACKGROUND and aim: Macrolide antibiotics are widely used in the treatment of suppurative lung diseases including cystic fibrosis (CF), the most common inherited fatal disease in the Caucasian population. This condition is characterized by secondary Pseudomonas infection resulting in neutrophil infi...

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Main Authors: Alexander L. Pukhalsky, Galina V. Shmarina, Nikolai I. Kapranov, Svetlana N. Kokarovtseva, Daria Pukhalskaya, Natalia J. Kashirskaja
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350410001688495
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author Alexander L. Pukhalsky
Galina V. Shmarina
Nikolai I. Kapranov
Svetlana N. Kokarovtseva
Daria Pukhalskaya
Natalia J. Kashirskaja
author_facet Alexander L. Pukhalsky
Galina V. Shmarina
Nikolai I. Kapranov
Svetlana N. Kokarovtseva
Daria Pukhalskaya
Natalia J. Kashirskaja
author_sort Alexander L. Pukhalsky
collection DOAJ
description BACKGROUND and aim: Macrolide antibiotics are widely used in the treatment of suppurative lung diseases including cystic fibrosis (CF), the most common inherited fatal disease in the Caucasian population. This condition is characterized by secondary Pseudomonas infection resulting in neutrophil infiltration within the airways. The aim of the study was to investigate the evolution of inflammatory process in CF patients receiving long-term clarithromycin therapy.
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institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2004-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-f5d0752ef12f4fb9b62094b4cc7f73622025-02-03T05:58:20ZengWileyMediators of Inflammation0962-93511466-18612004-01-0113211111710.1080/09629350410001688495Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung diseaseAlexander L. Pukhalsky0Galina V. Shmarina1Nikolai I. Kapranov2Svetlana N. Kokarovtseva3Daria Pukhalskaya4Natalia J. Kashirskaja5Research Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaResearch Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaResearch Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaResearch Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaResearch Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaResearch Centre for Medical Genetics, 1 Moskvorechie Street, Moscow 115478, RussiaBACKGROUND and aim: Macrolide antibiotics are widely used in the treatment of suppurative lung diseases including cystic fibrosis (CF), the most common inherited fatal disease in the Caucasian population. This condition is characterized by secondary Pseudomonas infection resulting in neutrophil infiltration within the airways. The aim of the study was to investigate the evolution of inflammatory process in CF patients receiving long-term clarithromycin therapy.http://dx.doi.org/10.1080/09629350410001688495
spellingShingle Alexander L. Pukhalsky
Galina V. Shmarina
Nikolai I. Kapranov
Svetlana N. Kokarovtseva
Daria Pukhalskaya
Natalia J. Kashirskaja
Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
Mediators of Inflammation
title Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
title_full Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
title_fullStr Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
title_full_unstemmed Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
title_short Anti-inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
title_sort anti inflammatory and immunomodulating effects of clarithromycin in patients with cystic fibrosis lung disease
url http://dx.doi.org/10.1080/09629350410001688495
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