New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications
This review highlights the recent development in the management of acute pancreatitis in the area of antibiotic prophylaxis, management of necrosis and correlation with SARS-CoV-2 infection. The evidence from recent studies has not shown a significant benefit of administration of antibiotic prophyl...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2025-02-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/57627 |
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| author | Aleksandra Woźniak Michał Jakub Cioch Julia Nowak Kamil Hermanowicz Urszula Kaczmarska Katarzyna Doman Agnieszka Najdek Daria Oleksy Dawid Komada Marcin Mycyk |
| author_facet | Aleksandra Woźniak Michał Jakub Cioch Julia Nowak Kamil Hermanowicz Urszula Kaczmarska Katarzyna Doman Agnieszka Najdek Daria Oleksy Dawid Komada Marcin Mycyk |
| author_sort | Aleksandra Woźniak |
| collection | DOAJ |
| description |
This review highlights the recent development in the management of acute pancreatitis in the area of antibiotic prophylaxis, management of necrosis and correlation with SARS-CoV-2 infection. The evidence from recent studies has not shown a significant benefit of administration of antibiotic prophylaxis in acute pancreatitis. Additionally, a few trials draw attention to the disadvantages of prophylactic use of antibiotics. However, in this area more trials have to be conducted. When it comes to management of necrosis, the recent data recommends a postponed drainage. Delayed procedure is considered now as preferential treatment. Furthermore, delayed drainage is associated with fewer interventions and necrosectomies compared to immediate drainage. There is still insufficient data to confirm the influence of SARS-CoV-2 infection on the development and course of pancreatitis. Special attention should be brought to all COVID-19 patients presenting with gastrointestinal symptoms. Measurement of amylase and/or lipase levels in the serum is recommended for preliminary diagnosis. If suspicion arises, full diagnosis of acute pancreatitis should be conducted for early implementation of supportive treatment.
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| format | Article |
| id | doaj-art-f5c5870bad414b4c8eca14361d33ea1e |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-f5c5870bad414b4c8eca14361d33ea1e2025-02-12T08:17:53ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-02-017810.12775/JEHS.2025.78.57627New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implicationsAleksandra Woźniak0https://orcid.org/0009-0004-7769-9865Michał Jakub Cioch1https://orcid.org/0009-0007-1555-3336Julia Nowak2https://orcid.org/0009-0009-5954-8138Kamil Hermanowicz3https://orcid.org/0009-0007-0844-1424Urszula Kaczmarska4https://orcid.org/0009-0007-2986-5760Katarzyna Doman5https://orcid.org/0009-0005-1022-490XAgnieszka Najdek6https://orcid.org/0009-0000-1112-3864Daria Oleksy7https://orcid.org/0009-0004-4492-3752Dawid Komada8https://orcid.org/0009-0009-6015-8292Marcin Mycyk9https://orcid.org/0009-0001-2553-3327Faculty of Medicine, Medical University of Lodz, al. Tadeusza Kościuszki 4, 90-419, Łódź, Poland Centrum Medyczne LUX MED al. Pokoju 18c, 31-564 Kraków, Poland RAW-MEDICA NZOZ, Słowackiego 68, 96-200 Rawa Mazowiecka, Poland SPZOZ w Zelowie, Żeromskiego 21, 97-425 Zelów, Poland ZOZ Ropczyce 39-100 Ropczyce, ul. Ks. Kard. St. Wyszyńskiego 54, Poland NZOZ MEDICUS, ul. Opiesińska 10-12, 98-220 Zduńska Wola, Poland University Clinical Hospital no. 2 of The Medical University of Lodz, ul. Żeromskiego 113, 90-549 Łódź, Poland Przychodnia Zespołu Lekarzy Rodzinnych LEKMED s.c. Czerwonego Krzyża 2, 63-000 Środa Wielkopolska, Poland Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie, ul. Złotej Jesieni 1, 31-826 Kraków, Poland Piotr Pelcer Klinika Zdrowia Sp. z o.o. Filia Kębłowo, ul. Chłopska 13, 84-242 Kębłowo, Poland This review highlights the recent development in the management of acute pancreatitis in the area of antibiotic prophylaxis, management of necrosis and correlation with SARS-CoV-2 infection. The evidence from recent studies has not shown a significant benefit of administration of antibiotic prophylaxis in acute pancreatitis. Additionally, a few trials draw attention to the disadvantages of prophylactic use of antibiotics. However, in this area more trials have to be conducted. When it comes to management of necrosis, the recent data recommends a postponed drainage. Delayed procedure is considered now as preferential treatment. Furthermore, delayed drainage is associated with fewer interventions and necrosectomies compared to immediate drainage. There is still insufficient data to confirm the influence of SARS-CoV-2 infection on the development and course of pancreatitis. Special attention should be brought to all COVID-19 patients presenting with gastrointestinal symptoms. Measurement of amylase and/or lipase levels in the serum is recommended for preliminary diagnosis. If suspicion arises, full diagnosis of acute pancreatitis should be conducted for early implementation of supportive treatment. https://apcz.umk.pl/JEHS/article/view/57627Acute pancreatitisantibiotic prophylaxismanagement of necrosisCOVID-19 |
| spellingShingle | Aleksandra Woźniak Michał Jakub Cioch Julia Nowak Kamil Hermanowicz Urszula Kaczmarska Katarzyna Doman Agnieszka Najdek Daria Oleksy Dawid Komada Marcin Mycyk New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications Journal of Education, Health and Sport Acute pancreatitis antibiotic prophylaxis management of necrosis COVID-19 |
| title | New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications |
| title_full | New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications |
| title_fullStr | New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications |
| title_full_unstemmed | New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications |
| title_short | New perspectives in the management of acute pancreatitis – focus on antibiotic prophylaxis, management of necrosis and COVID-19 implications |
| title_sort | new perspectives in the management of acute pancreatitis focus on antibiotic prophylaxis management of necrosis and covid 19 implications |
| topic | Acute pancreatitis antibiotic prophylaxis management of necrosis COVID-19 |
| url | https://apcz.umk.pl/JEHS/article/view/57627 |
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