Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review

Aquagenic wrinkling of the palms (AWP) is a rare transient dermatological disorder, characterized by an extreme and early wrinkling and pruning of the palms that occurs within a few minutes of exposure to water. Greater awareness of AWP is needed since the vast majority of AWP cases are linked with...

Full description

Saved in:
Bibliographic Details
Main Authors: Maryam K. Alsoweilem, Rasha H. Alsheikh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Family and Community Medicine
Subjects:
Online Access:https://journals.lww.com/10.4103/jfcm.jfcm_217_24
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823858664878899200
author Maryam K. Alsoweilem
Rasha H. Alsheikh
author_facet Maryam K. Alsoweilem
Rasha H. Alsheikh
author_sort Maryam K. Alsoweilem
collection DOAJ
description Aquagenic wrinkling of the palms (AWP) is a rare transient dermatological disorder, characterized by an extreme and early wrinkling and pruning of the palms that occurs within a few minutes of exposure to water. Greater awareness of AWP is needed since the vast majority of AWP cases are linked with cystic fibrosis (CF) and CF carrier state. Initial assessment of AWP cases can be done in a primary care setting. A comprehensive medical history and physical examination should be done upon the diagnosis of AWP with additional investigations based on patients’ presentation. We report two cases of AWP diagnosed at a family medicine center in Dammam, Saudi Arabia. The first case was related to the use of ibuprofen and discounting this medication led to a marked improvement in the patient’s symptoms. The second case was related to primary palmar hyperhidrosis that was managed successfully with topical 20% aluminum chloride.
format Article
id doaj-art-f5b8cf4f708e4ef3aeb1a12c6e399753
institution Kabale University
issn 2229-340X
language English
publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Family and Community Medicine
spelling doaj-art-f5b8cf4f708e4ef3aeb1a12c6e3997532025-02-11T10:39:24ZengWolters Kluwer Medknow PublicationsJournal of Family and Community Medicine2229-340X2025-01-01321747710.4103/jfcm.jfcm_217_24Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature reviewMaryam K. AlsoweilemRasha H. AlsheikhAquagenic wrinkling of the palms (AWP) is a rare transient dermatological disorder, characterized by an extreme and early wrinkling and pruning of the palms that occurs within a few minutes of exposure to water. Greater awareness of AWP is needed since the vast majority of AWP cases are linked with cystic fibrosis (CF) and CF carrier state. Initial assessment of AWP cases can be done in a primary care setting. A comprehensive medical history and physical examination should be done upon the diagnosis of AWP with additional investigations based on patients’ presentation. We report two cases of AWP diagnosed at a family medicine center in Dammam, Saudi Arabia. The first case was related to the use of ibuprofen and discounting this medication led to a marked improvement in the patient’s symptoms. The second case was related to primary palmar hyperhidrosis that was managed successfully with topical 20% aluminum chloride.https://journals.lww.com/10.4103/jfcm.jfcm_217_24aluminum chlorideaquagenic wrinkling of the palmscystic fibrosisibuprofenpalmar hyperhidrosisskin pruningskin wrinkling
spellingShingle Maryam K. Alsoweilem
Rasha H. Alsheikh
Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
Journal of Family and Community Medicine
aluminum chloride
aquagenic wrinkling of the palms
cystic fibrosis
ibuprofen
palmar hyperhidrosis
skin pruning
skin wrinkling
title Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
title_full Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
title_fullStr Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
title_full_unstemmed Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
title_short Aquagenic wrinkling of the palms: A report of two cases from a family medicine setting in Eastern Saudi Arabia and literature review
title_sort aquagenic wrinkling of the palms a report of two cases from a family medicine setting in eastern saudi arabia and literature review
topic aluminum chloride
aquagenic wrinkling of the palms
cystic fibrosis
ibuprofen
palmar hyperhidrosis
skin pruning
skin wrinkling
url https://journals.lww.com/10.4103/jfcm.jfcm_217_24
work_keys_str_mv AT maryamkalsoweilem aquagenicwrinklingofthepalmsareportoftwocasesfromafamilymedicinesettingineasternsaudiarabiaandliteraturereview
AT rashahalsheikh aquagenicwrinklingofthepalmsareportoftwocasesfromafamilymedicinesettingineasternsaudiarabiaandliteraturereview