Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis
Quinoxalin-2-one (1) reacts with ethyl acetoacetate in trifluoroacetic acid (TFA) to form 3-(2-oxopropylideno)-3,4-dihydroquinoxaline-2-one (2) and 3-(3-oxo-3,4- dihydroquinoxaline-2-(1H)-ylidene)methylquinoxaline-2-(1H)-one (3). The reaction product 3 was also obtained by heating the compound 1 wit...
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| Language: | English |
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Ural Federal University
2022-01-01
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| Series: | Chimica Techno Acta |
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| Online Access: | https://chimicatechnoacta.ru/article/view/5477 |
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| author | Y. A. Azev O. S. Koptyaeva A. A. Mkrtchan T. A. Pospelova |
| author_facet | Y. A. Azev O. S. Koptyaeva A. A. Mkrtchan T. A. Pospelova |
| author_sort | Y. A. Azev |
| collection | DOAJ |
| description | Quinoxalin-2-one (1) reacts with ethyl acetoacetate in trifluoroacetic acid (TFA) to form 3-(2-oxopropylideno)-3,4-dihydroquinoxaline-2-one (2) and 3-(3-oxo-3,4- dihydroquinoxaline-2-(1H)-ylidene)methylquinoxaline-2-(1H)-one (3). The reaction product 3 was also obtained by heating the compound 1 with acetone in the presence of TFA. |
| format | Article |
| id | doaj-art-f5ae61d64506410eaaabb0fc77bf67cb |
| institution | Kabale University |
| issn | 2411-1414 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Ural Federal University |
| record_format | Article |
| series | Chimica Techno Acta |
| spelling | doaj-art-f5ae61d64506410eaaabb0fc77bf67cb2025-08-20T03:25:29ZengUral Federal UniversityChimica Techno Acta2411-14142022-01-019110.15826/chimtech.2022.9.1.034253Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysisY. A. Azev0O. S. Koptyaeva1A. A. Mkrtchan2T. A. Pospelova3Ural Federal UniversityUral Federal UniversityUral Federal UniversityUral Federal UniversityQuinoxalin-2-one (1) reacts with ethyl acetoacetate in trifluoroacetic acid (TFA) to form 3-(2-oxopropylideno)-3,4-dihydroquinoxaline-2-one (2) and 3-(3-oxo-3,4- dihydroquinoxaline-2-(1H)-ylidene)methylquinoxaline-2-(1H)-one (3). The reaction product 3 was also obtained by heating the compound 1 with acetone in the presence of TFA.https://chimicatechnoacta.ru/article/view/5477quinoxaline-2-oneethyl acetoacetatenucleophilic substitution of hydrogenvicarious substitutionacid catalysis |
| spellingShingle | Y. A. Azev O. S. Koptyaeva A. A. Mkrtchan T. A. Pospelova Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis Chimica Techno Acta quinoxaline-2-one ethyl acetoacetate nucleophilic substitution of hydrogen vicarious substitution acid catalysis |
| title | Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis |
| title_full | Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis |
| title_fullStr | Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis |
| title_full_unstemmed | Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis |
| title_short | Features of -C-C- coupling of quinoxaline-2-one with ethyl acetoacetate under acid catalysis |
| title_sort | features of c c coupling of quinoxaline 2 one with ethyl acetoacetate under acid catalysis |
| topic | quinoxaline-2-one ethyl acetoacetate nucleophilic substitution of hydrogen vicarious substitution acid catalysis |
| url | https://chimicatechnoacta.ru/article/view/5477 |
| work_keys_str_mv | AT yaazev featuresofcccouplingofquinoxaline2onewithethylacetoacetateunderacidcatalysis AT oskoptyaeva featuresofcccouplingofquinoxaline2onewithethylacetoacetateunderacidcatalysis AT aamkrtchan featuresofcccouplingofquinoxaline2onewithethylacetoacetateunderacidcatalysis AT tapospelova featuresofcccouplingofquinoxaline2onewithethylacetoacetateunderacidcatalysis |