Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Prioritizing Parkinson’s disease risk genes in genome-wide association loci

Abstract Many drug targets in ongoing Parkinson’s disease (PD) clinical trials have strong genetic links. While genome-wide association studies (GWAS) nominate regions associated with disease, pinpointing causal genes is challenging. Our aim was to prioritize additional druggable genes underlying PD...

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Main Authors: Lara M. Lange, Catalina Cerquera-Cleves, Marijn Schipper, Georgia Panagiotaropoulou, Alice Braun, Julia Kraft, Swapnil Awasthi, Nathaniel Bell, Danielle Posthuma, Stephan Ripke, Cornelis Blauwendraat, Karl Heilbron
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00933-0
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