Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications

Conductive hydrogels provide a flexible platform technology that enables the development of personalized materials for various neuronal diagnostic and therapeutic applications, combining the complementary properties of conductive materials and hydrogels. By ensuring conductivity through conductive m...

Full description

Saved in:
Bibliographic Details
Main Authors: Xin‐Yu Xue, Lu Han, He‐Qing Cai, Kou Zhang, Zhi‐Cheng Sun, Ru‐Ping Liu, Tian‐Hao Wang, Fu‐Hong Pan, Wei‐Tao Man, Dong Wang, Juan Liu
Format: Article
Language:English
Published: Wiley-VCH 2025-08-01
Series:Small Structures
Subjects:
Online Access:https://doi.org/10.1002/sstr.202400696
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850036413977853952
author Xin‐Yu Xue
Lu Han
He‐Qing Cai
Kou Zhang
Zhi‐Cheng Sun
Ru‐Ping Liu
Tian‐Hao Wang
Fu‐Hong Pan
Wei‐Tao Man
Dong Wang
Juan Liu
author_facet Xin‐Yu Xue
Lu Han
He‐Qing Cai
Kou Zhang
Zhi‐Cheng Sun
Ru‐Ping Liu
Tian‐Hao Wang
Fu‐Hong Pan
Wei‐Tao Man
Dong Wang
Juan Liu
author_sort Xin‐Yu Xue
collection DOAJ
description Conductive hydrogels provide a flexible platform technology that enables the development of personalized materials for various neuronal diagnostic and therapeutic applications, combining the complementary properties of conductive materials and hydrogels. By ensuring conductivity through conductive materials, hydrogels largely compensate for the rigidity of traditional inorganic conductive materials, making them a suitable substitute. To adapt to different working environments, conductive hydrogels exhibit excellent properties, such as mechanical properties, adhesion, and biocompatibility, which further expand their applications. This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term stability and scalability of production.
format Article
id doaj-art-f543459ef307430d8dfb3ecf98bd3fba
institution DOAJ
issn 2688-4062
language English
publishDate 2025-08-01
publisher Wiley-VCH
record_format Article
series Small Structures
spelling doaj-art-f543459ef307430d8dfb3ecf98bd3fba2025-08-20T02:57:08ZengWiley-VCHSmall Structures2688-40622025-08-0168n/an/a10.1002/sstr.202400696Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to ApplicationsXin‐Yu Xue0Lu Han1He‐Qing Cai2Kou Zhang3Zhi‐Cheng Sun4Ru‐Ping Liu5Tian‐Hao Wang6Fu‐Hong Pan7Wei‐Tao Man8Dong Wang9Juan Liu10Beijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaBeijing Engineering Research Center of Printed Electronics Beijing Institute of Graphic Communication Beijing 102600 ChinaDepartment of Neurosurgery Beijing Tsinghua Changgung Hospital School of Clinical Medicine Tsinghua University Beijing 102218 ChinaState Key Laboratory of Digital Medical Engineering Key Laboratory of Biomedical Engineering of Hainan Province School of Biomedical Engineering Hainan University Sanya 572025 ChinaHepato‐Pancreato‐Biliary Center Beijing Tsinghua Changgung Hospital Key Laboratory of Digital Intelligence Hepatology (Ministry of Education/Beijing) School of Clinical Medicine Tsinghua University Beijing 102218 ChinaConductive hydrogels provide a flexible platform technology that enables the development of personalized materials for various neuronal diagnostic and therapeutic applications, combining the complementary properties of conductive materials and hydrogels. By ensuring conductivity through conductive materials, hydrogels largely compensate for the rigidity of traditional inorganic conductive materials, making them a suitable substitute. To adapt to different working environments, conductive hydrogels exhibit excellent properties, such as mechanical properties, adhesion, and biocompatibility, which further expand their applications. This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term stability and scalability of production.https://doi.org/10.1002/sstr.202400696bioelectronicsconductive hydrogelsneural interfaces
spellingShingle Xin‐Yu Xue
Lu Han
He‐Qing Cai
Kou Zhang
Zhi‐Cheng Sun
Ru‐Ping Liu
Tian‐Hao Wang
Fu‐Hong Pan
Wei‐Tao Man
Dong Wang
Juan Liu
Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
Small Structures
bioelectronics
conductive hydrogels
neural interfaces
title Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
title_full Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
title_fullStr Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
title_full_unstemmed Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
title_short Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
title_sort conductive hydrogel based neural interfaces from fabrication methods properties to applications
topic bioelectronics
conductive hydrogels
neural interfaces
url https://doi.org/10.1002/sstr.202400696
work_keys_str_mv AT xinyuxue conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT luhan conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT heqingcai conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT kouzhang conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT zhichengsun conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT rupingliu conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT tianhaowang conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT fuhongpan conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT weitaoman conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT dongwang conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications
AT juanliu conductivehydrogelbasedneuralinterfacesfromfabricationmethodspropertiestoapplications