Pathological Spectrum of Vascular Malformations of the Central Nervous System: A Single Institution Experience of a Decade

Background Vascular malformations (VMs) of the central nervous system comprise a variety of lesions that could affect the arteries, veins, or capillaries. Materials and Methods We analyzed the histopathological features of all the VMs diagnosed at our centre over a decade. Resu...

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Main Authors: Shrithi Karanth, Shilpa Rao, Amey Savardekar, Aravind HR, Nupur Pruthi, Arimapamagan Arivazhagan, Dhananjaya I. Bhat, Dwarakanath Srinivas, Bhagvatula Indira Devi, Sampath Somanna, Anita Mahadevan
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-03-01
Series:Indian Journal of Neurosurgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749141
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Summary:Background Vascular malformations (VMs) of the central nervous system comprise a variety of lesions that could affect the arteries, veins, or capillaries. Materials and Methods We analyzed the histopathological features of all the VMs diagnosed at our centre over a decade. Results Intracranial VM included arteriovenous malformation (AVM) (53%), cerebral cavernous malformations (CCMs) (45%), capillary telangiectasia (2%), venous angioma (0.5%), and arteriovenous fistula (AVF) (0.5%). In spinal VMs, capillary telangiectasia (40%) were the most common, followed by cavernomas (34%), AVF (16%), and AVMs and venous angiomas (5%). Clinical presentation varied from focal deficit to features of raised intracranial tension. Conclusion Imaging and histopathology plays an important role in the diagnosis and management of VMs. Histopathological examination is essential for characterization of the VMs, which influences the prognosis.
ISSN:2277-954X
2277-9167