Epidemiology of anemia in patients with stages 3-5D chronic kidney disease: a cross-sectional study in Harbin,Northeast China
Objective To determine the prevalence of anemia in subjects with chronic kidney disease( CKD) 3-5,reveal the characteristics of anemia in those patients,and provide data for promoting this situation. M ethods This was an epidemiological,cross-sectional,single-center study under routine clinical prac...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2017-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57917778&Fpath=home&index=0 |
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| Summary: | Objective To determine the prevalence of anemia in subjects with chronic kidney disease( CKD) 3-5,reveal the characteristics of anemia in those patients,and provide data for promoting this situation. M ethods This was an epidemiological,cross-sectional,single-center study under routine clinical practice conditions. Data of 8 5 9 CKD 3-5 patients admitted to the First Affiliated Hospital of Harbin Medical University or in its hemodialysis center from October 2 0 1 1 to August2 0 1 5 were used to understand the prevalence of anemia in those patients( stage 3 : n = 2 4 1; stage4 : n = 1 9 5; stage 5 : n = 2 4 3; stage 5 D: n = 1 8 0). Results The mean hemoglobin( Hb) value for patients with CKD 3 was 1 1 9. 0 ± 2 3. 2 g/L,compared to 1 0 2. 3 ± 2 0. 4 g/L in patients with CKD 4,to 8 6. 1 ± 1 9. 3 g/L with CKD 5 ND( CKD 5 not on dialysis),and to 1 0 1. 6 ± 1 8. 2 g/L with CKD 5 D( CKD 5 on dialysis). There was statistically significant difference among the groups( F = 103. 48,P < 0. 01). The overall prevalence of anemia was 43. 2%,71. 3%,95. 9%,and7 8. 9 % in patients with CKD 3,CKD 4,CKD 5 ND and CKD 5 HD,respectively. The prevalence ofmoderate anemia [9 0 g/L≤ Hb < 1 2 0 g/L( male)/1 1 0 g/L( female) ] was 8 3. 7 %( CKD 3),6 1. 9 %( CKD 4),5 1. 1 %( CKD 5),and 7 1. 1 %( CKD 5 D) respectively. According to the standard of anemia in China,the patients with normocytic anemia accounted for 6 6. 7 %. The linear regression showed that Hb( g/L) = 7 9. 8 0 + 0. 9 1 × e GFR [m L·min-1·( 1. 73 m2)-1]( R =0. 5 9,F = 5 7. 7 3,P < 0. 0 1). Conclusions We found that the prevalence of anemia was increased with the raised prevalence of CKD 3-5. Normocytic and normochromic anemia is the most common form in patients with CKD 3-5 D,in accordance with its pathogeneses. In patients with CKD3-5,mean Hb level was decreased as e GFR was linearly decreased. |
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| ISSN: | 1671-2390 |