A study on diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging in patients with prostate cancer
Background: This study aims to evaluate the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), and their combination in prostate cancer patients. Methods: 134 patients with prostatic diseases (61 cases with benign prostatic hy...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MRE Press
2025-07-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://oss.jomh.org/files/article/20250730-590/pdf/JOMH2024121901.pdf |
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| Summary: | Background: This study aims to evaluate the diagnostic efficacy of
dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI),
diffusion-weighted imaging (DWI), and their combination in prostate cancer
patients. Methods: 134 patients with prostatic diseases (61 cases with
benign prostatic hyperplasia and 73 cases with prostate cancer) admitted to our
hospital from February 2022 to February 2024 were retrospectively analyzed.
DCE-MRI and DWI were performed. A comparison was made between both groups based
on needle biopsy results, DWI index, DCE-MRI index, detection results and
diagnostic efficacy. Receiver operating characteristic (ROC) curves were plotted
to examine diagnostic performance differences between different diagnostic
methods. Result: In the prostate cancer group, DWI high signal ratio,
volume transfer constant (Ktrans) and rate constant (Kep) were significantly
higher, while in the DWI group slightly high signal intensity, low mixed signal
ratio and extravascular extracellular volume fraction (Ve) were lower (p
< 0.05). DCE-MRI and DWI combined had the largest area under the curve (AUC) on
the ROC curve (p < 0.05). Conclusions: A combination of
DCE-MRI and DWI for prostate cancer results yielded significantly higher
diagnostic accuracy than either modality alone. Clinically, this combined
approach can guide prostate cancer diagnosis and treatment with significant
clinical value. |
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| ISSN: | 1875-6867 1875-6859 |