Biological effect of acupuncture on peripheral facial paralysis
Peripheral facial paralysis is the dominant treatment disease of acupuncture. A large number of studies have proved the effectiveness of acupuncture in the treatment of peripheral facial paralysis. However, the underlying biological effect remains in an exploratory phase. This article will sort out...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1516904/full |
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| author | Wenwen Duan Dan Chen Zubo Huang Yue Zeng Shanshan Liu Chao Wang Hao Zhou |
| author_facet | Wenwen Duan Dan Chen Zubo Huang Yue Zeng Shanshan Liu Chao Wang Hao Zhou |
| author_sort | Wenwen Duan |
| collection | DOAJ |
| description | Peripheral facial paralysis is the dominant treatment disease of acupuncture. A large number of studies have proved the effectiveness of acupuncture in the treatment of peripheral facial paralysis. However, the underlying biological effect remains in an exploratory phase. This article will sort out and summarize the existing research mechanisms from the following aspects: inflammatory response, immune regulation, neurotransmitters, immune response, facial microcirculation, oxidative stress, changes in nerve structure and function, specificity of acupoints, acupuncture intervention time, and other potential mechanisms aiming to provide a scientific foundation for the role of acupuncture in the treatment of peripheral facial paralysis. Furthermore, the review discusses future directions for mechanistic research based on existing findings. |
| format | Article |
| id | doaj-art-f4fc36c1c2cf4792bf870f8d20a02025 |
| institution | DOAJ |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-f4fc36c1c2cf4792bf870f8d20a020252025-08-20T03:13:51ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-04-011610.3389/fneur.2025.15169041516904Biological effect of acupuncture on peripheral facial paralysisWenwen Duan0Dan Chen1Zubo Huang2Yue Zeng3Shanshan Liu4Chao Wang5Hao Zhou6School of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acupuncture-Moxibustion and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSichuan Clinical Research Center for Sub-Health, Sichuan Integrative Medicine Hospital, Chengdu, ChinaSichuan Clinical Research Center for Sub-Health, Sichuan Integrative Medicine Hospital, Chengdu, ChinaSichuan Clinical Research Center for Sub-Health, Sichuan Integrative Medicine Hospital, Chengdu, ChinaSichuan Clinical Research Center for Sub-Health, Sichuan Integrative Medicine Hospital, Chengdu, ChinaSichuan Clinical Research Center for Sub-Health, Sichuan Integrative Medicine Hospital, Chengdu, ChinaPeripheral facial paralysis is the dominant treatment disease of acupuncture. A large number of studies have proved the effectiveness of acupuncture in the treatment of peripheral facial paralysis. However, the underlying biological effect remains in an exploratory phase. This article will sort out and summarize the existing research mechanisms from the following aspects: inflammatory response, immune regulation, neurotransmitters, immune response, facial microcirculation, oxidative stress, changes in nerve structure and function, specificity of acupoints, acupuncture intervention time, and other potential mechanisms aiming to provide a scientific foundation for the role of acupuncture in the treatment of peripheral facial paralysis. Furthermore, the review discusses future directions for mechanistic research based on existing findings.https://www.frontiersin.org/articles/10.3389/fneur.2025.1516904/fullacupunctureperipheral facial paralysisneuroinflammationmolecular neurobiologybiological effect |
| spellingShingle | Wenwen Duan Dan Chen Zubo Huang Yue Zeng Shanshan Liu Chao Wang Hao Zhou Biological effect of acupuncture on peripheral facial paralysis Frontiers in Neurology acupuncture peripheral facial paralysis neuroinflammation molecular neurobiology biological effect |
| title | Biological effect of acupuncture on peripheral facial paralysis |
| title_full | Biological effect of acupuncture on peripheral facial paralysis |
| title_fullStr | Biological effect of acupuncture on peripheral facial paralysis |
| title_full_unstemmed | Biological effect of acupuncture on peripheral facial paralysis |
| title_short | Biological effect of acupuncture on peripheral facial paralysis |
| title_sort | biological effect of acupuncture on peripheral facial paralysis |
| topic | acupuncture peripheral facial paralysis neuroinflammation molecular neurobiology biological effect |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1516904/full |
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