Invasive fungal rhinosinusitis in patients with diabetes
Introduction: We report the clinical and radiological features as well as outcomes of invasive fungal rhinosinusitis in patients with diabetes from a tertiary care center in North India. Methodology: All patients admitted with a diagnosis of invasive fungal rhinosinusitis with pre-existing or ne...
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The Journal of Infection in Developing Countries
2018-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/9699 |
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| author | Nishant Raizada Viveka P Jyotsna Devasenathipathy Kandasamy Immaculata Xess Alok Thakar Nikhil Tandon |
| author_facet | Nishant Raizada Viveka P Jyotsna Devasenathipathy Kandasamy Immaculata Xess Alok Thakar Nikhil Tandon |
| author_sort | Nishant Raizada |
| collection | DOAJ |
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Introduction: We report the clinical and radiological features as well as outcomes of invasive fungal rhinosinusitis in patients with diabetes from a tertiary care center in North India.
Methodology: All patients admitted with a diagnosis of invasive fungal rhinosinusitis with pre-existing or newly diagnosed diabetes from 1st January 2008 to 31st December 2015 were included. Hospital records were used to identify clinical features, biochemical investigations and treatment modalities used. The imaging findings were reported at baseline, 30, 60,90 and 120 days of admission and progression of disease was reported as static, worse or improved. The outcomes were sight loss and survival at end of hospital stay.
Results: 22 patients of invasive fungal sinusitis and diabetes were identified. At presentation, 5 had ketoacidosis, all of whom died at the end of hospital stay. Loss of vision in one eye was seen in 70% cases. The survival at end of hospital stay was 72.7% and at six months after end of study period was 57.8%. No patients had radiological improvement at day 30 imaging (including those who subsequently improved).
Conclusion: Radiological improvement is not apparent before two months of therapy. Ketoacidosis is a predictor of mortality in invasive fungal sinusitis with diabetes.
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| format | Article |
| id | doaj-art-f4e4f66debcf4806b119a2433741b499 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-f4e4f66debcf4806b119a2433741b4992025-08-20T02:27:15ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802018-09-01120910.3855/jidc.9699Invasive fungal rhinosinusitis in patients with diabetesNishant Raizada0Viveka P Jyotsna1Devasenathipathy Kandasamy2Immaculata Xess3Alok Thakar4Nikhil Tandon5All India Institute of Medical Sciences, New Delhi, IndiaAll India Institute of Medical Sciences, New Delhi, IndiaAll India Institute of Medical Sciences, New Delhi, IndiaAll India Institute of Medical Sciences, New Delhi, IndiaAll India Institute of Medical Sciences, New Delhi, IndiaAll India Institute of Medical Sciences, New Delhi, India Introduction: We report the clinical and radiological features as well as outcomes of invasive fungal rhinosinusitis in patients with diabetes from a tertiary care center in North India. Methodology: All patients admitted with a diagnosis of invasive fungal rhinosinusitis with pre-existing or newly diagnosed diabetes from 1st January 2008 to 31st December 2015 were included. Hospital records were used to identify clinical features, biochemical investigations and treatment modalities used. The imaging findings were reported at baseline, 30, 60,90 and 120 days of admission and progression of disease was reported as static, worse or improved. The outcomes were sight loss and survival at end of hospital stay. Results: 22 patients of invasive fungal sinusitis and diabetes were identified. At presentation, 5 had ketoacidosis, all of whom died at the end of hospital stay. Loss of vision in one eye was seen in 70% cases. The survival at end of hospital stay was 72.7% and at six months after end of study period was 57.8%. No patients had radiological improvement at day 30 imaging (including those who subsequently improved). Conclusion: Radiological improvement is not apparent before two months of therapy. Ketoacidosis is a predictor of mortality in invasive fungal sinusitis with diabetes. https://jidc.org/index.php/journal/article/view/9699invasive fungal rhinosinusitisdiabetesliposomal amphotericin Bmucormycosis |
| spellingShingle | Nishant Raizada Viveka P Jyotsna Devasenathipathy Kandasamy Immaculata Xess Alok Thakar Nikhil Tandon Invasive fungal rhinosinusitis in patients with diabetes Journal of Infection in Developing Countries invasive fungal rhinosinusitis diabetes liposomal amphotericin B mucormycosis |
| title | Invasive fungal rhinosinusitis in patients with diabetes |
| title_full | Invasive fungal rhinosinusitis in patients with diabetes |
| title_fullStr | Invasive fungal rhinosinusitis in patients with diabetes |
| title_full_unstemmed | Invasive fungal rhinosinusitis in patients with diabetes |
| title_short | Invasive fungal rhinosinusitis in patients with diabetes |
| title_sort | invasive fungal rhinosinusitis in patients with diabetes |
| topic | invasive fungal rhinosinusitis diabetes liposomal amphotericin B mucormycosis |
| url | https://jidc.org/index.php/journal/article/view/9699 |
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