Paranasal Rosai-Dorfman Disease with Osseous Destruction

Rosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown etiology typically characterized by cervical lymphadenopathy. Extranodal involvement often manifests in the head and neck region. We present a 10-year-old male who presented to our hospital with left epiphora from an aggre...

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Main Authors: Kevin Hur, Changxing Liu, Jeffrey A. Koempel
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2017/1453097
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author Kevin Hur
Changxing Liu
Jeffrey A. Koempel
author_facet Kevin Hur
Changxing Liu
Jeffrey A. Koempel
author_sort Kevin Hur
collection DOAJ
description Rosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown etiology typically characterized by cervical lymphadenopathy. Extranodal involvement often manifests in the head and neck region. We present a 10-year-old male who presented to our hospital with left epiphora from an aggressive paranasal mass invading the left orbit with osseous destruction. The mass was surgically biopsied and debulked with histopathological examination revealing Rosai-Dorfman disease. Although rarely found in the sinuses, Rosai-Dorfman disease should be considered when evaluating sinonasal masses.
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institution Kabale University
issn 2090-6765
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language English
publishDate 2017-01-01
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series Case Reports in Otolaryngology
spelling doaj-art-f4bf013a5bf54cedb2ef3fd715b07eeb2025-08-20T03:25:23ZengWileyCase Reports in Otolaryngology2090-67652090-67732017-01-01201710.1155/2017/14530971453097Paranasal Rosai-Dorfman Disease with Osseous DestructionKevin Hur0Changxing Liu1Jeffrey A. Koempel2Caruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USACaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USADivision of Otolaryngology, Head and Neck Surgery, Children’s Hospital Los Angeles, Los Angeles, CA 90027, USARosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown etiology typically characterized by cervical lymphadenopathy. Extranodal involvement often manifests in the head and neck region. We present a 10-year-old male who presented to our hospital with left epiphora from an aggressive paranasal mass invading the left orbit with osseous destruction. The mass was surgically biopsied and debulked with histopathological examination revealing Rosai-Dorfman disease. Although rarely found in the sinuses, Rosai-Dorfman disease should be considered when evaluating sinonasal masses.http://dx.doi.org/10.1155/2017/1453097
spellingShingle Kevin Hur
Changxing Liu
Jeffrey A. Koempel
Paranasal Rosai-Dorfman Disease with Osseous Destruction
Case Reports in Otolaryngology
title Paranasal Rosai-Dorfman Disease with Osseous Destruction
title_full Paranasal Rosai-Dorfman Disease with Osseous Destruction
title_fullStr Paranasal Rosai-Dorfman Disease with Osseous Destruction
title_full_unstemmed Paranasal Rosai-Dorfman Disease with Osseous Destruction
title_short Paranasal Rosai-Dorfman Disease with Osseous Destruction
title_sort paranasal rosai dorfman disease with osseous destruction
url http://dx.doi.org/10.1155/2017/1453097
work_keys_str_mv AT kevinhur paranasalrosaidorfmandiseasewithosseousdestruction
AT changxingliu paranasalrosaidorfmandiseasewithosseousdestruction
AT jeffreyakoempel paranasalrosaidorfmandiseasewithosseousdestruction