Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics

Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics

ObjectiveThis study aimed to explore the clinical relevance of Human Epidermal Growth Factor Receptor 2 (HER2) in urothelial carcinoma (UC) and its association with glycolytic metabolic markers, insulin resistance, and beta-cell function, shedding light on potential therapies targeting both HER2 pat...

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Bibliographic Details
Main Authors: Andong Guo, Chenrui Wu, Jishuang Cao, Kejia Zhu, Sentai Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
urothelial carcinoma
HER2
glycolytic metabolism
lactate dehydrogenase
therapeutic targets
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1521889/full
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