AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms

Protocol Summary We have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into a library preparation station without losing the potential of an open platform. Implementation of AG-NGS does not require programming experi...

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Main Authors: Sergio Callejas, Rebeca Álvarez, Alberto Benguria, Ana Dopazo
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/000114504
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author Sergio Callejas
Rebeca Álvarez
Alberto Benguria
Ana Dopazo
author_facet Sergio Callejas
Rebeca Álvarez
Alberto Benguria
Ana Dopazo
author_sort Sergio Callejas
collection DOAJ
description Protocol Summary We have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into a library preparation station without losing the potential of an open platform. Implementation of AG-NGS does not require programming experience, and the application has also been designed to minimize implementation costs. Automated library preparation with AG-NGS generated high-quality libraries from different samples, demonstrating its efficiency, and all quality control parameters fell within the range of optimal values.
format Article
id doaj-art-f4bce2d8b95f4043be18fa2edbb7b853
institution OA Journals
issn 0736-6205
1940-9818
language English
publishDate 2017-01-01
publisher Taylor & Francis Group
record_format Article
series BioTechniques
spelling doaj-art-f4bce2d8b95f4043be18fa2edbb7b8532025-08-20T02:25:58ZengTaylor & Francis GroupBioTechniques0736-62051940-98182017-01-01621xvi10.2144/000114504AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platformsSergio Callejas0Rebeca Álvarez1Alberto Benguria2Ana Dopazo31Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain1Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain1Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain1Spanish National Center for Cardiovascular Research (CNIC), Madrid, SpainProtocol Summary We have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into a library preparation station without losing the potential of an open platform. Implementation of AG-NGS does not require programming experience, and the application has also been designed to minimize implementation costs. Automated library preparation with AG-NGS generated high-quality libraries from different samples, demonstrating its efficiency, and all quality control parameters fell within the range of optimal values.https://www.future-science.com/doi/10.2144/000114504
spellingShingle Sergio Callejas
Rebeca Álvarez
Alberto Benguria
Ana Dopazo
AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
BioTechniques
title AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
title_full AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
title_fullStr AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
title_full_unstemmed AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
title_short AG-NGS: A powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms
title_sort ag ngs a powerful and user friendly computing application for the semi automated preparation of next generation sequencing libraries using open liquid handling platforms
url https://www.future-science.com/doi/10.2144/000114504
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AT albertobenguria agngsapowerfulanduserfriendlycomputingapplicationforthesemiautomatedpreparationofnextgenerationsequencinglibrariesusingopenliquidhandlingplatforms
AT anadopazo agngsapowerfulanduserfriendlycomputingapplicationforthesemiautomatedpreparationofnextgenerationsequencinglibrariesusingopenliquidhandlingplatforms