Role of hypoxia-related genes and immune infiltration in intervertebral disc degeneration: molecular mechanisms and diagnostic potential

Role of hypoxia-related genes and immune infiltration in intervertebral disc degeneration: molecular mechanisms and diagnostic potential

ObjectiveTo investigate the role of hypoxia-related genes and immune infiltration in intervertebral disc degeneration (IDD) to identify molecular mechanisms and potential therapeutic targets.MethodsUsing GEO data, IDD-related gene expression datasets were analyzed for hypoxia-related differentially...

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Bibliographic Details
Main Authors:	Kai Zhou, Jiaxiang Zhou, XianJin Luo, Yan Chen, Jian Ao, Wei Wu, Bo Yang, Zhongyuan He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	hypoxia intervertebral disc degeneration biomarkers immune infiltration gene expression
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1606905/full
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