Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus

The Hepatitis E virus (HEV) is responsible for causing Hepatitis E, a zoonotic disease that has emerged as a significant global health concern, accounting for about 20 million infections and 70,000 deaths annually. Although it is often recognized as a disease that is acute in low-income countries, H...

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Main Authors: Mariana Alves Elois, Catielen Paula Pavi, Yasmin Ferreira Souza Hoffmann Jempierre, Giulia Von Tönnemann Pilati, Lucas Zanchetta, Henrique Borges da Silva Grisard, Nerea García, David Rodríguez-Lázaro, Gislaine Fongaro
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/5/998
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author Mariana Alves Elois
Catielen Paula Pavi
Yasmin Ferreira Souza Hoffmann Jempierre
Giulia Von Tönnemann Pilati
Lucas Zanchetta
Henrique Borges da Silva Grisard
Nerea García
David Rodríguez-Lázaro
Gislaine Fongaro
author_facet Mariana Alves Elois
Catielen Paula Pavi
Yasmin Ferreira Souza Hoffmann Jempierre
Giulia Von Tönnemann Pilati
Lucas Zanchetta
Henrique Borges da Silva Grisard
Nerea García
David Rodríguez-Lázaro
Gislaine Fongaro
author_sort Mariana Alves Elois
collection DOAJ
description The Hepatitis E virus (HEV) is responsible for causing Hepatitis E, a zoonotic disease that has emerged as a significant global health concern, accounting for about 20 million infections and 70,000 deaths annually. Although it is often recognized as a disease that is acute in low-income countries, HEV has also been recognized as a zoonotic disease in high-income countries. The zoonotic transmission requires flexible approaches to effectively monitor the virus, vectors, and reservoirs. However, the environmental monitoring of HEV presents additional challenges due to limitations in current detection methods, making it difficult to accurately assess the global prevalence of the virus. These challenges hinder efforts to fully understand the scope of the disease and to implement effective control measures. This review will explore these and other critical concerns, addressing gaps in HEV research and highlighting the need for improved strategies in the monitoring, prevention, and management of Hepatitis E using a One Health approach.
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publishDate 2025-04-01
publisher MDPI AG
record_format Article
series Microorganisms
spelling doaj-art-f486464bc2f84a6dac64237be5bebca32025-08-20T02:34:01ZengMDPI AGMicroorganisms2076-26072025-04-0113599810.3390/microorganisms13050998Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E VirusMariana Alves Elois0Catielen Paula Pavi1Yasmin Ferreira Souza Hoffmann Jempierre2Giulia Von Tönnemann Pilati3Lucas Zanchetta4Henrique Borges da Silva Grisard5Nerea García6David Rodríguez-Lázaro7Gislaine Fongaro8Laboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilDepartment of Animal Health, Complutense University of Madrid, 28040 Madrid, SpainMicrobiology Division, Faculty of Sciences, University of Burgos, 09001 Burgos, SpainLaboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, BrazilThe Hepatitis E virus (HEV) is responsible for causing Hepatitis E, a zoonotic disease that has emerged as a significant global health concern, accounting for about 20 million infections and 70,000 deaths annually. Although it is often recognized as a disease that is acute in low-income countries, HEV has also been recognized as a zoonotic disease in high-income countries. The zoonotic transmission requires flexible approaches to effectively monitor the virus, vectors, and reservoirs. However, the environmental monitoring of HEV presents additional challenges due to limitations in current detection methods, making it difficult to accurately assess the global prevalence of the virus. These challenges hinder efforts to fully understand the scope of the disease and to implement effective control measures. This review will explore these and other critical concerns, addressing gaps in HEV research and highlighting the need for improved strategies in the monitoring, prevention, and management of Hepatitis E using a One Health approach.https://www.mdpi.com/2076-2607/13/5/998Hepatitis E virussurveillancedetectionenvironmentOne Health
spellingShingle Mariana Alves Elois
Catielen Paula Pavi
Yasmin Ferreira Souza Hoffmann Jempierre
Giulia Von Tönnemann Pilati
Lucas Zanchetta
Henrique Borges da Silva Grisard
Nerea García
David Rodríguez-Lázaro
Gislaine Fongaro
Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
Microorganisms
Hepatitis E virus
surveillance
detection
environment
One Health
title Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
title_full Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
title_fullStr Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
title_full_unstemmed Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
title_short Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
title_sort trends and challenges in the detection and environmental surveillance of the hepatitis e virus
topic Hepatitis E virus
surveillance
detection
environment
One Health
url https://www.mdpi.com/2076-2607/13/5/998
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