5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens

Strawberry Fusarium wilt (SFW) is a systematic soil-borne disease caused by Fusarium oxysporum f. sp. fragaria (Fof), which infects the vascular bundles, blocking water and nutrient transport from roots to the aboveground. It is a severe pathogen which spreads rapidly and destroys strawberry product...

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Main Authors: Hao Yang, Jianting Zhang, Haiwen Zhang, Rongxiang Cao, Donglan Tang, Liangju Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-11-01
Series:Horticultural Plant Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468014123001784
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author Hao Yang
Jianting Zhang
Haiwen Zhang
Rongxiang Cao
Donglan Tang
Liangju Wang
author_facet Hao Yang
Jianting Zhang
Haiwen Zhang
Rongxiang Cao
Donglan Tang
Liangju Wang
author_sort Hao Yang
collection DOAJ
description Strawberry Fusarium wilt (SFW) is a systematic soil-borne disease caused by Fusarium oxysporum f. sp. fragaria (Fof), which infects the vascular bundles, blocking water and nutrient transport from roots to the aboveground. It is a severe pathogen which spreads rapidly and destroys strawberry production. Finding a way to control this disease is of great scientific value and practical importance. In this study, three fungi were isolated from the vascular tissues of sick strawberries in the field. After DNA sequencing, they were identified as Fof, Aspergillus fumigatus and Trichoderma harzianum, respectively, among which the first two are pathogens and the third is a probiotic. All fungi were controlled by thiophanate-methyl (TM), a commercial fungicide. On PDA medium, 20 mg·L−1 5-aminolevulinic acid (ALA), a natural non-protein amino acid, promoted T. harzianum proliferation, but inhibited Fof and A. fumigatus. In confrontation test, the growth of Fof or A. fumigatus was inhibited by T. harzianum and exogenous ALA promoted T. harzianum growth but significantly inhibited the pathogen growth. When three species of fungi were separately or combinedly inoculated on healthy strawberry plants, T. harzianum promoted plant growth and development while Fof or A. fumigatus caused growth retardation, where Fof directly caused leaf yellowing and plant wilting. When the plants inoculated with different fungus were treated with ALA, the results turned out that ALA alleviated SFW symptoms by bidirectionally promoting T. harzianum proliferation and inhibiting Fof and A. fumigatus. Thus, ALA might be used in comprehensively controlling SFW in strawberry industry.
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issn 2468-0141
language English
publishDate 2024-11-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Horticultural Plant Journal
spelling doaj-art-f47b6ca52bc34061bd000f7caec86f2c2025-08-20T02:11:38ZengKeAi Communications Co., Ltd.Horticultural Plant Journal2468-01412024-11-011061349136110.1016/j.hpj.2023.02.0145-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogensHao Yang0Jianting Zhang1Haiwen Zhang2Rongxiang Cao3Donglan Tang4Liangju Wang5College of Horticulture, Nanjing Agricultural University, Nanjing, Jiangsu 21095, ChinaCollege of Horticulture, Nanjing Agricultural University, Nanjing, Jiangsu 21095, ChinaCollege of Horticulture, Nanjing Agricultural University, Nanjing, Jiangsu 21095, ChinaInstitute of Nanjing Agricultural Sciences, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu 210046, ChinaInstitute of Nanjing Agricultural Sciences, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu 210046, ChinaCollege of Horticulture, Nanjing Agricultural University, Nanjing, Jiangsu 21095, China; Corresponding author.Strawberry Fusarium wilt (SFW) is a systematic soil-borne disease caused by Fusarium oxysporum f. sp. fragaria (Fof), which infects the vascular bundles, blocking water and nutrient transport from roots to the aboveground. It is a severe pathogen which spreads rapidly and destroys strawberry production. Finding a way to control this disease is of great scientific value and practical importance. In this study, three fungi were isolated from the vascular tissues of sick strawberries in the field. After DNA sequencing, they were identified as Fof, Aspergillus fumigatus and Trichoderma harzianum, respectively, among which the first two are pathogens and the third is a probiotic. All fungi were controlled by thiophanate-methyl (TM), a commercial fungicide. On PDA medium, 20 mg·L−1 5-aminolevulinic acid (ALA), a natural non-protein amino acid, promoted T. harzianum proliferation, but inhibited Fof and A. fumigatus. In confrontation test, the growth of Fof or A. fumigatus was inhibited by T. harzianum and exogenous ALA promoted T. harzianum growth but significantly inhibited the pathogen growth. When three species of fungi were separately or combinedly inoculated on healthy strawberry plants, T. harzianum promoted plant growth and development while Fof or A. fumigatus caused growth retardation, where Fof directly caused leaf yellowing and plant wilting. When the plants inoculated with different fungus were treated with ALA, the results turned out that ALA alleviated SFW symptoms by bidirectionally promoting T. harzianum proliferation and inhibiting Fof and A. fumigatus. Thus, ALA might be used in comprehensively controlling SFW in strawberry industry.http://www.sciencedirect.com/science/article/pii/S24680141230017845-Aminolevulinic acidAntagonistic effectDisease controlFusarium oxysporum f. sp. fragaria (Fof)Strawberry Fusarium wilt (SFW)Trichoderma harzianum
spellingShingle Hao Yang
Jianting Zhang
Haiwen Zhang
Rongxiang Cao
Donglan Tang
Liangju Wang
5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
Horticultural Plant Journal
5-Aminolevulinic acid
Antagonistic effect
Disease control
Fusarium oxysporum f. sp. fragaria (Fof)
Strawberry Fusarium wilt (SFW)
Trichoderma harzianum
title 5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
title_full 5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
title_fullStr 5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
title_full_unstemmed 5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
title_short 5-Aminolevulinic acid against strawberry Fusarium wilt: Bidirectional regulation of biocontrol agents and pathogens
title_sort 5 aminolevulinic acid against strawberry fusarium wilt bidirectional regulation of biocontrol agents and pathogens
topic 5-Aminolevulinic acid
Antagonistic effect
Disease control
Fusarium oxysporum f. sp. fragaria (Fof)
Strawberry Fusarium wilt (SFW)
Trichoderma harzianum
url http://www.sciencedirect.com/science/article/pii/S2468014123001784
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AT haiwenzhang 5aminolevulinicacidagainststrawberryfusariumwiltbidirectionalregulationofbiocontrolagentsandpathogens
AT rongxiangcao 5aminolevulinicacidagainststrawberryfusariumwiltbidirectionalregulationofbiocontrolagentsandpathogens
AT donglantang 5aminolevulinicacidagainststrawberryfusariumwiltbidirectionalregulationofbiocontrolagentsandpathogens
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