Structural evolution of mechanical heart valves (review)

Prosthetic heart valves are widely used biomedical devices. The need for these prostheses is increasing due to the increasing life expectancy of the general population and the consequent incidence of age-related degenerative valvular defects. However, even though mechanical prosthetic valves have be...

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Main Authors: M. A. Lepilin, A. V. Bogachev-Prokophiev, М. О. Zhulkov, D. S. Khvan, D. A. Sirota, A. G. Makaev, A. V. Protopopov, A. S. Grenadyorov, Kh. A. Agaeva, A. М. Chernyavskiy
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2024-04-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/1709
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author M. A. Lepilin
A. V. Bogachev-Prokophiev
М. О. Zhulkov
D. S. Khvan
D. A. Sirota
A. G. Makaev
A. V. Protopopov
A. S. Grenadyorov
Kh. A. Agaeva
A. М. Chernyavskiy
author_facet M. A. Lepilin
A. V. Bogachev-Prokophiev
М. О. Zhulkov
D. S. Khvan
D. A. Sirota
A. G. Makaev
A. V. Protopopov
A. S. Grenadyorov
Kh. A. Agaeva
A. М. Chernyavskiy
author_sort M. A. Lepilin
collection DOAJ
description Prosthetic heart valves are widely used biomedical devices. The need for these prostheses is increasing due to the increasing life expectancy of the general population and the consequent incidence of age-related degenerative valvular defects. However, even though mechanical prosthetic valves have been significantly modernized over the last decades, they are still associated with several life-threatening complications, the main one being thrombosis. Addressing this problem is challenging and requires collaboration between bioengineering and cardiothoracic surgery. Thus, the problem of creating the most adapted model of prosthetic heart valve (PHV) turns out to be at the confluence of sciences – medicine, biology, applied mechanics, mathematical modeling, etc. Today, it seems clear that the engineering ideas for hemodynamic adaptation of PHV models have been fully developed. However, research in the field of materials science, as well as a search for surface modification methods, remain a pressing bioengineering challenge.
format Article
id doaj-art-f4589f8563b84dc4868bd03e7a782874
institution Kabale University
issn 1995-1191
language Russian
publishDate 2024-04-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-f4589f8563b84dc4868bd03e7a7828742025-08-20T03:38:19ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912024-04-0126117819010.15825/1995-1191-2024-1-178-1901220Structural evolution of mechanical heart valves (review)M. A. Lepilin0A. V. Bogachev-Prokophiev1М. О. Zhulkov2D. S. Khvan3D. A. Sirota4A. G. Makaev5A. V. Protopopov6A. S. Grenadyorov7Kh. A. Agaeva8A. М. Chernyavskiy9Meshalkin National Medical Research CenterMeshalkin National Medical Research CenterMeshalkin National Medical Research CenterMeshalkin National Medical Research CenterMeshalkin National Medical Research Center; Novosibirsk State Medical UniversityMeshalkin National Medical Research CenterMeshalkin National Medical Research CenterInstitute of High Current ElectronicsMeshalkin National Medical Research CenterMeshalkin National Medical Research Center; Novosibirsk State Medical UniversityProsthetic heart valves are widely used biomedical devices. The need for these prostheses is increasing due to the increasing life expectancy of the general population and the consequent incidence of age-related degenerative valvular defects. However, even though mechanical prosthetic valves have been significantly modernized over the last decades, they are still associated with several life-threatening complications, the main one being thrombosis. Addressing this problem is challenging and requires collaboration between bioengineering and cardiothoracic surgery. Thus, the problem of creating the most adapted model of prosthetic heart valve (PHV) turns out to be at the confluence of sciences – medicine, biology, applied mechanics, mathematical modeling, etc. Today, it seems clear that the engineering ideas for hemodynamic adaptation of PHV models have been fully developed. However, research in the field of materials science, as well as a search for surface modification methods, remain a pressing bioengineering challenge.https://journal.transpl.ru/vtio/article/view/1709heart valvesmechanical valvesacquired heart diseases
spellingShingle M. A. Lepilin
A. V. Bogachev-Prokophiev
М. О. Zhulkov
D. S. Khvan
D. A. Sirota
A. G. Makaev
A. V. Protopopov
A. S. Grenadyorov
Kh. A. Agaeva
A. М. Chernyavskiy
Structural evolution of mechanical heart valves (review)
Вестник трансплантологии и искусственных органов
heart valves
mechanical valves
acquired heart diseases
title Structural evolution of mechanical heart valves (review)
title_full Structural evolution of mechanical heart valves (review)
title_fullStr Structural evolution of mechanical heart valves (review)
title_full_unstemmed Structural evolution of mechanical heart valves (review)
title_short Structural evolution of mechanical heart valves (review)
title_sort structural evolution of mechanical heart valves review
topic heart valves
mechanical valves
acquired heart diseases
url https://journal.transpl.ru/vtio/article/view/1709
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AT avbogachevprokophiev structuralevolutionofmechanicalheartvalvesreview
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AT dasirota structuralevolutionofmechanicalheartvalvesreview
AT agmakaev structuralevolutionofmechanicalheartvalvesreview
AT avprotopopov structuralevolutionofmechanicalheartvalvesreview
AT asgrenadyorov structuralevolutionofmechanicalheartvalvesreview
AT khaagaeva structuralevolutionofmechanicalheartvalvesreview
AT amchernyavskiy structuralevolutionofmechanicalheartvalvesreview