Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt
Background: different treatment modalities used for treating head and neck cancer are associated with oral side effects that affect patients’ quality of life. This study aims to detect the prevalence of different oral side effects associated with chemo and radiotherapy in head and neck cancer. Metho...
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024000232 |
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| author | Dalia Mohamed abo el Fadel Yasmine Kamal Ashraf Hamed Hassouna Amal Ali |
| author_facet | Dalia Mohamed abo el Fadel Yasmine Kamal Ashraf Hamed Hassouna Amal Ali |
| author_sort | Dalia Mohamed abo el Fadel |
| collection | DOAJ |
| description | Background: different treatment modalities used for treating head and neck cancer are associated with oral side effects that affect patients’ quality of life. This study aims to detect the prevalence of different oral side effects associated with chemo and radiotherapy in head and neck cancer. Methodology: A cross-sectional study was conducted on 294 head and neck cancer patients, clinical examination of the oral cavity was done in which oral mucositis, xerostomia, altered taste sensation, pain, oral fungal infections, and dysphagia were documented and graded as well as Edmonton Assessment Symptom Scale and University of Washington questionnaire v.4 (UWQOL). Results: The prevalence of oral side effects among 294 HNC patients was 93.9%. The most common one was oral mucositis 97.3% followed by xerostomia 84.4%, while 64.6% had dysphagia,53.7% complained of altered taste sensation, and 19% had oral fungal infections and pain mean score of 4. Postoperative radiotherapy is associated with Grade (2) oral mucositis and dysphagia, radical radiotherapy is associated with Grade (1) oral mucositis and pain while severe dysphagia is associated with combined therapy. According to quality of life questionnaire, the best score reported by UWQOL v.4 was shoulder pain while the worst score was for anxiety and mood. There was worsening of physical and social domains of quality of life with chemoradiotherapy and overall patient condition. Conclusion: Head and neck cancer patients suffer from severe oral side effects influenced by the treatment modality and stage of the tumor affecting their quality of life. |
| format | Article |
| id | doaj-art-f458824428234a1399d95e0807a187c1 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-f458824428234a1399d95e0807a187c12025-01-09T06:15:14ZengElsevierOral Oncology Reports2772-90602024-06-0110100177Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in EgyptDalia Mohamed abo el Fadel0Yasmine Kamal1Ashraf Hamed Hassouna2Amal Ali3Cairo University, Oral Medicine Department, 9Z Sama towers- ring road, Qatamya, Cairo, Egypt; Corresponding author.Oral Medicine And Periodontology, Faculty of Dentistry, Cairo University, Cairo, EgyptRadio Oncology Department, NCI-Cairo University, EgyptOral Medicine And Periodontology, Faculty of Dentistry, Cairo University, Cairo, EgyptBackground: different treatment modalities used for treating head and neck cancer are associated with oral side effects that affect patients’ quality of life. This study aims to detect the prevalence of different oral side effects associated with chemo and radiotherapy in head and neck cancer. Methodology: A cross-sectional study was conducted on 294 head and neck cancer patients, clinical examination of the oral cavity was done in which oral mucositis, xerostomia, altered taste sensation, pain, oral fungal infections, and dysphagia were documented and graded as well as Edmonton Assessment Symptom Scale and University of Washington questionnaire v.4 (UWQOL). Results: The prevalence of oral side effects among 294 HNC patients was 93.9%. The most common one was oral mucositis 97.3% followed by xerostomia 84.4%, while 64.6% had dysphagia,53.7% complained of altered taste sensation, and 19% had oral fungal infections and pain mean score of 4. Postoperative radiotherapy is associated with Grade (2) oral mucositis and dysphagia, radical radiotherapy is associated with Grade (1) oral mucositis and pain while severe dysphagia is associated with combined therapy. According to quality of life questionnaire, the best score reported by UWQOL v.4 was shoulder pain while the worst score was for anxiety and mood. There was worsening of physical and social domains of quality of life with chemoradiotherapy and overall patient condition. Conclusion: Head and neck cancer patients suffer from severe oral side effects influenced by the treatment modality and stage of the tumor affecting their quality of life.http://www.sciencedirect.com/science/article/pii/S2772906024000232Head and neck cancerOral side-effectsRadiotherapyAnd chemotherapyPrevalenceUniversity of Washington questionnaire |
| spellingShingle | Dalia Mohamed abo el Fadel Yasmine Kamal Ashraf Hamed Hassouna Amal Ali Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt Oral Oncology Reports Head and neck cancer Oral side-effects Radiotherapy And chemotherapy Prevalence University of Washington questionnaire |
| title | Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt |
| title_full | Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt |
| title_fullStr | Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt |
| title_full_unstemmed | Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt |
| title_short | Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt |
| title_sort | prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment a cross sectional study in egypt |
| topic | Head and neck cancer Oral side-effects Radiotherapy And chemotherapy Prevalence University of Washington questionnaire |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024000232 |
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