The Impact of Migraine on Posterior Ocular Structures
Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as co...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/868967 |
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| author | Süleyman Demircan Mustafa Ataş Sevgi Arık Yüksel Melek D. Ulusoy İsa Yuvacı Hasan Basri Arifoğlu Burhan Başkan Gökmen Zararsız |
| author_facet | Süleyman Demircan Mustafa Ataş Sevgi Arık Yüksel Melek D. Ulusoy İsa Yuvacı Hasan Basri Arifoğlu Burhan Başkan Gökmen Zararsız |
| author_sort | Süleyman Demircan |
| collection | DOAJ |
| description | Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The RNFL and macular thicknesses were analysed with standard OCT protocol while choroidal thickness was analysed with EDI protocol in all subjects. Choroidal thickness was measured at the fovea, 1500 µm nasal and 1500 µm temporal to the fovea in a horizontal section. Results. The mean RNFL thickness for nasal and nasal inferior sectors was significantly thinner (P≤0.018) in the migraineurs’ eyes than in those of the controls, as was the mean choroid thickness at the fovea and measured points (P<0.0001). However, the mean macular thickness was not significantly different between the groups. Conclusions. This study suggests that migraine leads to a reduction in the peripapillary RNFL thickness and to thinning in choroidal structures. These findings can be explained by a chronic ischemic insult related to migraine pathogenic mechanisms and these findings are considered supportive of the relationship between glaucoma and migraine. |
| format | Article |
| id | doaj-art-f44f9b67ba8443b9a816653600f17d0b |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-f44f9b67ba8443b9a816653600f17d0b2025-02-03T01:11:32ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/868967868967The Impact of Migraine on Posterior Ocular StructuresSüleyman Demircan0Mustafa Ataş1Sevgi Arık Yüksel2Melek D. Ulusoy3İsa Yuvacı4Hasan Basri Arifoğlu5Burhan Başkan6Gökmen Zararsız7Kayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Neurology Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyKayseri Training and Research Hospital Eye Clinic, 38010 Kayseri, TurkeyBiostatistics Department, Erciyes University, 38039 Kayseri, TurkeyPurpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The RNFL and macular thicknesses were analysed with standard OCT protocol while choroidal thickness was analysed with EDI protocol in all subjects. Choroidal thickness was measured at the fovea, 1500 µm nasal and 1500 µm temporal to the fovea in a horizontal section. Results. The mean RNFL thickness for nasal and nasal inferior sectors was significantly thinner (P≤0.018) in the migraineurs’ eyes than in those of the controls, as was the mean choroid thickness at the fovea and measured points (P<0.0001). However, the mean macular thickness was not significantly different between the groups. Conclusions. This study suggests that migraine leads to a reduction in the peripapillary RNFL thickness and to thinning in choroidal structures. These findings can be explained by a chronic ischemic insult related to migraine pathogenic mechanisms and these findings are considered supportive of the relationship between glaucoma and migraine.http://dx.doi.org/10.1155/2015/868967 |
| spellingShingle | Süleyman Demircan Mustafa Ataş Sevgi Arık Yüksel Melek D. Ulusoy İsa Yuvacı Hasan Basri Arifoğlu Burhan Başkan Gökmen Zararsız The Impact of Migraine on Posterior Ocular Structures Journal of Ophthalmology |
| title | The Impact of Migraine on Posterior Ocular Structures |
| title_full | The Impact of Migraine on Posterior Ocular Structures |
| title_fullStr | The Impact of Migraine on Posterior Ocular Structures |
| title_full_unstemmed | The Impact of Migraine on Posterior Ocular Structures |
| title_short | The Impact of Migraine on Posterior Ocular Structures |
| title_sort | impact of migraine on posterior ocular structures |
| url | http://dx.doi.org/10.1155/2015/868967 |
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