Identification of low-molecular compounds that inhibit envelope formation of hepatitis B virus

Abstract Agents with novel mechanisms are clinically needed for the functional cure of chronic hepatitis B virus (HBV) infection. This study aimed to identify compounds that inhibit an interaction between large hepatitis B surface (LHBs) and hepatitis B core (HBc) proteins, which are considered to b...

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Bibliographic Details
Main Authors: Kosuke Sato, Jun Inoue, Masashi Ninomiya, Akitoshi Sano, Mio Tsuruoka, Masazumi Onuki, Satoko Sawahashi, Keishi Ouchi, Kotaro Doi, Kengo Watanabe, Atsushi Masamune
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10473-5
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