Methylglyoxal: A Key Factor for Diabetic Retinopathy and Its Effects on Retinal Damage

Methylglyoxal: A Key Factor for Diabetic Retinopathy and Its Effects on Retinal Damage

<b>Background:</b> Diabetic retinopathy is the most common retinal vascular disease, affecting the retina’s blood vessels and causing chronic inflammation, oxidative stress, and, ultimately, vision loss. Diabetes-induced elevated glucose levels increase glycolysis, the main methylglyoxal...

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Bibliographic Details
Main Authors: Vladlen Klochkov, Chi-Ming Chan, Wan-Wan Lin
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
methylglyoxal
diabetic retinopathy
oxidative stress
inflammation
autophagy
ER stress
Online Access:https://www.mdpi.com/2227-9059/12/11/2512
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