Integrated analysis of polytranscriptomics reveals TNFSF ligand genes in pancreatic cancer prognosis and immune regulation

Abstract The tumor necrosis factor (TNF) ligand superfamily plays a critical role in immune regulation and has emerged as a promising target in cancer immunotherapy. By binding to its receptor OX40 (CD134), TNFSF4 promotes the proliferation and survival of T cells and plays an important role in the...

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Bibliographic Details
Main Authors: Zhaoda Deng, Lincheng Li, Zitong Yang, Guineng Zeng, Rong Liu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Immunology
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Online Access:https://doi.org/10.1186/s12865-025-00733-4
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