Generalized anxiety disorder patients' cognitive control in affective contexts

BackgroundGrowing evidence suggests a relationship between deficits in cognitive control and anxiety. However, studies examining cognitive control within affective contexts (affective control) are limited, and the specific characteristics of affective control in patients with Generalized Anxiety Dis...

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Main Authors: Yuqi Shen, Shasha Zhu, Shiqi Liao, Yuqing Zhao, Zihan Lin, Ke Jiang, Wenjing Yan, Xinhua Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1506239/full
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author Yuqi Shen
Shasha Zhu
Shasha Zhu
Shiqi Liao
Yuqing Zhao
Yuqing Zhao
Zihan Lin
Ke Jiang
Wenjing Yan
Xinhua Shen
Xinhua Shen
author_facet Yuqi Shen
Shasha Zhu
Shasha Zhu
Shiqi Liao
Yuqing Zhao
Yuqing Zhao
Zihan Lin
Ke Jiang
Wenjing Yan
Xinhua Shen
Xinhua Shen
author_sort Yuqi Shen
collection DOAJ
description BackgroundGrowing evidence suggests a relationship between deficits in cognitive control and anxiety. However, studies examining cognitive control within affective contexts (affective control) are limited, and the specific characteristics of affective control in patients with Generalized Anxiety Disorder (GAD) remain unclear. This study investigated whether differences exist in cognitive control under affective contexts.MethodsWe conduct our research in a population of GAD patients (n = 50) and a healthy control group (n = 50). The affective flanker task measured affective inhibition, while the affective flexibility task assessed affective shifting capabilities.ResultsGAD patients exhibited abnormal affective inhibition, characterized by reduced proactive control related to target stimulus processing and enhanced reactive control associated with distractor resolution. Additionally, GAD patients demonstrated deficits in affective shifting, as indicated by significantly higher shifting costs in both non-affective and affective tasks compared to the healthy control group.ConclusionsThe findings reveal that GAD patients display poorer emotion recognition abilities, indicating deficits in affective control compared to healthy individuals. Our study underscores the importance of measuring affective control by delineating it into distinct components.
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publishDate 2025-05-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Psychiatry
spelling doaj-art-f411049ca0b64f4faae4e473789f42f72025-08-20T03:53:51ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-05-011610.3389/fpsyt.2025.15062391506239Generalized anxiety disorder patients' cognitive control in affective contextsYuqi Shen0Shasha Zhu1Shasha Zhu2Shiqi Liao3Yuqing Zhao4Yuqing Zhao5Zihan Lin6Ke Jiang7Wenjing Yan8Xinhua Shen9Xinhua Shen10Huzhou Third Municipal Hospital, the Affiliated Hospital of Wenzhou Medical University, Huzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaDepartment of Psychology, School of Mental Health, Wenzhou Medical University, Wenzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaDepartment of Psychology, School of Mental Health, Wenzhou Medical University, Wenzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaSchool of Mental Health, Wenzhou Medical University, Wenzhou, ChinaHuzhou Third Municipal Hospital, the Affiliated Hospital of Wenzhou Medical University, Huzhou, ChinaDepartment of Neurosis and Psychosomatic Diseases, Huzhou Third Municipal Hospital, Huzhou, ChinaBackgroundGrowing evidence suggests a relationship between deficits in cognitive control and anxiety. However, studies examining cognitive control within affective contexts (affective control) are limited, and the specific characteristics of affective control in patients with Generalized Anxiety Disorder (GAD) remain unclear. This study investigated whether differences exist in cognitive control under affective contexts.MethodsWe conduct our research in a population of GAD patients (n = 50) and a healthy control group (n = 50). The affective flanker task measured affective inhibition, while the affective flexibility task assessed affective shifting capabilities.ResultsGAD patients exhibited abnormal affective inhibition, characterized by reduced proactive control related to target stimulus processing and enhanced reactive control associated with distractor resolution. Additionally, GAD patients demonstrated deficits in affective shifting, as indicated by significantly higher shifting costs in both non-affective and affective tasks compared to the healthy control group.ConclusionsThe findings reveal that GAD patients display poorer emotion recognition abilities, indicating deficits in affective control compared to healthy individuals. Our study underscores the importance of measuring affective control by delineating it into distinct components.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1506239/fullgeneralized anxiety disorderaffective inhibitionaffective shiftingcognitive controlaffective control
spellingShingle Yuqi Shen
Shasha Zhu
Shasha Zhu
Shiqi Liao
Yuqing Zhao
Yuqing Zhao
Zihan Lin
Ke Jiang
Wenjing Yan
Xinhua Shen
Xinhua Shen
Generalized anxiety disorder patients' cognitive control in affective contexts
Frontiers in Psychiatry
generalized anxiety disorder
affective inhibition
affective shifting
cognitive control
affective control
title Generalized anxiety disorder patients' cognitive control in affective contexts
title_full Generalized anxiety disorder patients' cognitive control in affective contexts
title_fullStr Generalized anxiety disorder patients' cognitive control in affective contexts
title_full_unstemmed Generalized anxiety disorder patients' cognitive control in affective contexts
title_short Generalized anxiety disorder patients' cognitive control in affective contexts
title_sort generalized anxiety disorder patients cognitive control in affective contexts
topic generalized anxiety disorder
affective inhibition
affective shifting
cognitive control
affective control
url https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1506239/full
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