Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid.

Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid.

<h4>Background</h4>The diagnosis of primary ciliary dyskinesia (PCD) requires the analysis of ciliary function and ultrastructure. Diagnosis can be complicated by secondary effects on cilia such as damage during sampling, local inflammation or recent infection. To differentiate primary f...

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Bibliographic Details
Main Authors: Robert A Hirst, Claire L Jackson, Janice L Coles, Gwyneth Williams, Andrew Rutman, Patricia M Goggin, Elizabeth C Adam, Anthony Page, Hazel J Evans, Peter M Lackie, Christopher O'Callaghan, Jane S Lucas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089675&type=printable
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