Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis
Background. Subcutaneous fat necrosis (SFN) is a form of transient panniculitis that presents commonly in infants with a history of perinatal insult, particularly hypothermia. It is characterized by subcutaneous nodules and plaques that appear over bony prominences on cheeks, shoulders, buttock, and...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2020/5742394 |
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| author | Mitali Sahni Pooja Patel Akila Muthukumar |
| author_facet | Mitali Sahni Pooja Patel Akila Muthukumar |
| author_sort | Mitali Sahni |
| collection | DOAJ |
| description | Background. Subcutaneous fat necrosis (SFN) is a form of transient panniculitis that presents commonly in infants with a history of perinatal insult, particularly hypothermia. It is characterized by subcutaneous nodules and plaques that appear over bony prominences on cheeks, shoulders, buttock, and thighs. SFN is usually associated with various complications including hypercalcemia, thrombocytopenia, hypertriglyceridemia, and hyperglycemia. Case Presentation. We present a unique case of a female infant with a history of maternal chorioamnionitis who presented with SFN at 11 days of life with thrombocytosis. The platelet count decreased during the hospital stay, and thrombocytosis resolved over the course of the next two weeks. She did not have any other hematological or metabolic abnormalities associated with SFN. Conclusion. Infants with perinatal stress are at increased risk of developing SFN during the first month of life. Infants with a diagnosis of SFN should be monitored closely for various hematological and metabolic abnormalities that can have serious consequences. |
| format | Article |
| id | doaj-art-f3fd72069f574ca2aed1b529076d3203 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-f3fd72069f574ca2aed1b529076d32032025-08-20T03:25:45ZengWileyCase Reports in Hematology2090-65602090-65792020-01-01202010.1155/2020/57423945742394Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal ChorioamnionitisMitali Sahni0Pooja Patel1Akila Muthukumar2Pediatrix Medical Group, Sunrise Children’s Hospital, University of Nevada, Las Vegas, NV, USADepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USADepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USABackground. Subcutaneous fat necrosis (SFN) is a form of transient panniculitis that presents commonly in infants with a history of perinatal insult, particularly hypothermia. It is characterized by subcutaneous nodules and plaques that appear over bony prominences on cheeks, shoulders, buttock, and thighs. SFN is usually associated with various complications including hypercalcemia, thrombocytopenia, hypertriglyceridemia, and hyperglycemia. Case Presentation. We present a unique case of a female infant with a history of maternal chorioamnionitis who presented with SFN at 11 days of life with thrombocytosis. The platelet count decreased during the hospital stay, and thrombocytosis resolved over the course of the next two weeks. She did not have any other hematological or metabolic abnormalities associated with SFN. Conclusion. Infants with perinatal stress are at increased risk of developing SFN during the first month of life. Infants with a diagnosis of SFN should be monitored closely for various hematological and metabolic abnormalities that can have serious consequences.http://dx.doi.org/10.1155/2020/5742394 |
| spellingShingle | Mitali Sahni Pooja Patel Akila Muthukumar Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis Case Reports in Hematology |
| title | Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis |
| title_full | Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis |
| title_fullStr | Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis |
| title_full_unstemmed | Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis |
| title_short | Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis |
| title_sort | severe thrombocytosis in a newborn with subcutaneous fat necrosis and maternal chorioamnionitis |
| url | http://dx.doi.org/10.1155/2020/5742394 |
| work_keys_str_mv | AT mitalisahni severethrombocytosisinanewbornwithsubcutaneousfatnecrosisandmaternalchorioamnionitis AT poojapatel severethrombocytosisinanewbornwithsubcutaneousfatnecrosisandmaternalchorioamnionitis AT akilamuthukumar severethrombocytosisinanewbornwithsubcutaneousfatnecrosisandmaternalchorioamnionitis |