GPR139 agonist and antagonist differentially regulate retrieval and consolidation of fear memory in the zebrafish

GPR139 agonist and antagonist differentially regulate retrieval and consolidation of fear memory in the zebrafish

G protein-coupled receptor 139 (GPR139), a highly conserved orphan receptor, is predominantly expressed in the habenula of vertebrate species. Habenula is an ancient epithalamic structure, which is critical to comprehending adaptive behaviors in vertebrates. We have previously demonstrated the role...

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Bibliographic Details
Main Authors: Nisa Roy, Satoshi Ogawa, Sachiko Tsuda, Ishwar S. Parhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Neuroscience
Subjects:
GPR139
habenula
fear memory
calcium imaging
conditioned place avoidance
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1461148/full
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