Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report
Abstract Severe esophageal strictures resulting from chemoradiotherapy pose persistent therapeutic challenges despite the availability of treatments such as endoscopic balloon dilation and medications. Hyperbaric oxygen therapy (HBOT) has emerged as a promising treatment option for refractory radiat...
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| Format: | Article |
| Language: | English |
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Wiley
2025-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.70072 |
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| author | Tetsuyuki Tateda Hidezumi Kikuchi Keisuke Furusawa Yusuke Matsuoka Taka Asari Yohei Sawada Satoru Nakagawa Tatsuta Tetsuya Daisuke Chinda Hirotake Sakuraba |
| author_facet | Tetsuyuki Tateda Hidezumi Kikuchi Keisuke Furusawa Yusuke Matsuoka Taka Asari Yohei Sawada Satoru Nakagawa Tatsuta Tetsuya Daisuke Chinda Hirotake Sakuraba |
| author_sort | Tetsuyuki Tateda |
| collection | DOAJ |
| description | Abstract Severe esophageal strictures resulting from chemoradiotherapy pose persistent therapeutic challenges despite the availability of treatments such as endoscopic balloon dilation and medications. Hyperbaric oxygen therapy (HBOT) has emerged as a promising treatment option for refractory radiation‐induced injury to several organs. Herein, we present the case of a 79‐year‐old male patient with refractory radiation‐induced ulcerative esophageal strictures after chemoradiotherapy. Despite multiple interventions, including endoscopic balloon dilation, steroids, and proton‐pump inhibitors, the patient remained unable to tolerate oral intake. HBOT was initiated, leading to significant improvement in the esophageal ulcers and strictures within 1 month. HBOT was well tolerated; the patient experienced a sustained improvement in his quality of life. Two years after HBOT, esophagogastroduodenoscopy confirmed persistent improvement in esophageal ulcers and strictures. This case highlights the potential of HBOT as a therapeutic option for ulcerative esophageal strictures unresponsive to conventional treatments. |
| format | Article |
| id | doaj-art-f39ec6423ec849f2b626324b92a628fa |
| institution | DOAJ |
| issn | 2692-4609 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-f39ec6423ec849f2b626324b92a628fa2025-08-20T03:13:51ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.70072Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case reportTetsuyuki Tateda0Hidezumi Kikuchi1Keisuke Furusawa2Yusuke Matsuoka3Taka Asari4Yohei Sawada5Satoru Nakagawa6Tatsuta Tetsuya7Daisuke Chinda8Hirotake Sakuraba9Department of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanDivision of Endoscopy Hirosaki University Hospital Aomori JapanDepartment of Gastroenterology, Hematology, and Clinical Immunology Hirosaki University Graduate School of Medicine Aomori JapanAbstract Severe esophageal strictures resulting from chemoradiotherapy pose persistent therapeutic challenges despite the availability of treatments such as endoscopic balloon dilation and medications. Hyperbaric oxygen therapy (HBOT) has emerged as a promising treatment option for refractory radiation‐induced injury to several organs. Herein, we present the case of a 79‐year‐old male patient with refractory radiation‐induced ulcerative esophageal strictures after chemoradiotherapy. Despite multiple interventions, including endoscopic balloon dilation, steroids, and proton‐pump inhibitors, the patient remained unable to tolerate oral intake. HBOT was initiated, leading to significant improvement in the esophageal ulcers and strictures within 1 month. HBOT was well tolerated; the patient experienced a sustained improvement in his quality of life. Two years after HBOT, esophagogastroduodenoscopy confirmed persistent improvement in esophageal ulcers and strictures. This case highlights the potential of HBOT as a therapeutic option for ulcerative esophageal strictures unresponsive to conventional treatments.https://doi.org/10.1002/deo2.70072chemoradiotherapydigestive system endoscopydilationesophageal stenosishyperbaric oxygenation |
| spellingShingle | Tetsuyuki Tateda Hidezumi Kikuchi Keisuke Furusawa Yusuke Matsuoka Taka Asari Yohei Sawada Satoru Nakagawa Tatsuta Tetsuya Daisuke Chinda Hirotake Sakuraba Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report DEN Open chemoradiotherapy digestive system endoscopy dilation esophageal stenosis hyperbaric oxygenation |
| title | Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report |
| title_full | Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report |
| title_fullStr | Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report |
| title_full_unstemmed | Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report |
| title_short | Successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy: A case report |
| title_sort | successful treatment with hyperbaric oxygen therapy for ulcerative esophageal stricture after chemoradiotherapy a case report |
| topic | chemoradiotherapy digestive system endoscopy dilation esophageal stenosis hyperbaric oxygenation |
| url | https://doi.org/10.1002/deo2.70072 |
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