Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in the transforming growth factor-beta...

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Bibliographic Details
Main Authors: Rayra P. Santiago, Camylla V. B. Figueiredo, Luciana M. Fiuza, Sètondji C. M. A. Yahouédéhou, Rodrigo M. Oliveira, Milena M. Aleluia, Suellen P. Carvalho, Cleverson A. Fonseca, Valma M. L. Nascimento, Larissa C. Rocha, Caroline C. Guarda, Marilda S. Gonçalves
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/3185015
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