A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.

A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.

<h4>Background</h4>Ebola virus (EBOV) caused more than 11,000 deaths during the 2013-2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can produce little to no symptoms in others. A better understa...

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Main Authors: Bobby Brooke Herrera, Donald J Hamel, Philip Oshun, Rolake Akinsola, Alani S Akanmu, Charlotte A Chang, Philomena Eromon, Onikepe Folarin, Kayode T Adeyemi, Christian T Happi, Yichen Lu, Folasade Ogunsola, Phyllis J Kanki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0006530&type=printable
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