Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case

The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology. The disease must be differentiated from primary B-cell lymphoma of the skin, anaplastic large cell CD30+ skin lymphoma, tumor st...

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Main Authors: N. V. Zilberberg, M. M. Kokhan, G. D. Safonova, O. G. Rimar, I. A. Kuklin, V. A. Iglikov
Format: Article
Language:Russian
Published: Open Systems Publication 2021-07-01
Series:Лечащий Врач
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Online Access:https://journal.lvrach.ru/jour/article/view/751
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author N. V. Zilberberg
M. M. Kokhan
G. D. Safonova
O. G. Rimar
I. A. Kuklin
V. A. Iglikov
author_facet N. V. Zilberberg
M. M. Kokhan
G. D. Safonova
O. G. Rimar
I. A. Kuklin
V. A. Iglikov
author_sort N. V. Zilberberg
collection DOAJ
description The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology. The disease must be differentiated from primary B-cell lymphoma of the skin, anaplastic large cell CD30+ skin lymphoma, tumor stage of fungal mycosis, pseudolymphoma. The importance of clinical oncological alertness of doctors and the need for clinical and laboratory examination of a patient using modern histological and immunohistochemical research methods are shown. The article presents a case of diagnostics of a rare variant of primary skin lymphoma of cellular skin lymphoma – primary cutaneous CD4+ small/medium sized pleomorphic T-cell lymphoma in a 70-year-old patient. The diagnosis was verified by pathomorphological and immunohistochemical studies of the biopsy of the affected skin.
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issn 1560-5175
2687-1181
language Russian
publishDate 2021-07-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-f3480c4134f340bcbc67f8a3ebf456692025-08-20T03:20:17ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-07-0105434510.51793/OS.2021.32.20.009750Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical caseN. V. Zilberberg0M. M. Kokhan1G. D. Safonova2O. G. Rimar3I. A. Kuklin4V. A. Iglikov5Ural Scientific Research Institute of Dermatovenerology and ImmunopathologyUral Scientific Research Institute of Dermatovenerology and ImmunopathologyUral Scientific Research Institute of Dermatovenerology and ImmunopathologyUral Scientific Research Institute of Dermatovenerology and ImmunopathologyUral Scientific Research Institute of Dermatovenerology and ImmunopathologyState Medical Institution «Chelyabinsk Regional Skin and Venereological Dispensary No. 3»The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology. The disease must be differentiated from primary B-cell lymphoma of the skin, anaplastic large cell CD30+ skin lymphoma, tumor stage of fungal mycosis, pseudolymphoma. The importance of clinical oncological alertness of doctors and the need for clinical and laboratory examination of a patient using modern histological and immunohistochemical research methods are shown. The article presents a case of diagnostics of a rare variant of primary skin lymphoma of cellular skin lymphoma – primary cutaneous CD4+ small/medium sized pleomorphic T-cell lymphoma in a 70-year-old patient. The diagnosis was verified by pathomorphological and immunohistochemical studies of the biopsy of the affected skin.https://journal.lvrach.ru/jour/article/view/751t-cell lymphomadisease patterndiagnosisimmunohistochemical studies
spellingShingle N. V. Zilberberg
M. M. Kokhan
G. D. Safonova
O. G. Rimar
I. A. Kuklin
V. A. Iglikov
Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
Лечащий Врач
t-cell lymphoma
disease pattern
diagnosis
immunohistochemical studies
title Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
title_full Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
title_fullStr Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
title_full_unstemmed Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
title_short Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case
title_sort primary cutaneous cd4 pleomorphic small to medium cell t cell lymphoma a clinical case
topic t-cell lymphoma
disease pattern
diagnosis
immunohistochemical studies
url https://journal.lvrach.ru/jour/article/view/751
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AT gdsafonova primarycutaneouscd4pleomorphicsmalltomediumcelltcelllymphomaaclinicalcase
AT ogrimar primarycutaneouscd4pleomorphicsmalltomediumcelltcelllymphomaaclinicalcase
AT iakuklin primarycutaneouscd4pleomorphicsmalltomediumcelltcelllymphomaaclinicalcase
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