Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics

Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics

Abstract Telomeres and telomerase play crucial roles in the initiation and progression of cancer. As biomarkers, they aid in distinguishing benign from malignant tissues. Despite the promising therapeutic potential of targeting telomeres and telomerase for therapy, translating this concept from the...

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Bibliographic Details
Main Authors: Songting Shou, Ayidana Maolan, Di Zhang, Xiaochen Jiang, Fudong Liu, Yi Li, Xiyuan Zhang, En Geer, Zhenqing Pu, Baojin Hua, Qiujun Guo, Xing Zhang, Bo Pang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Experimental Hematology & Oncology
Subjects:
Telomeres
Telomere shortening
Cancer
Online Access:https://doi.org/10.1186/s40164-025-00597-9
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