In silico analysis of the action of saturated, monounsaturated, and polyunsaturated fatty acids against Echinococcus granulosus fatty-acid-binding protein 1 [version 2; peer review: 1 approved, 2 approved with reservations]

In silico analysis of the action of saturated, monounsaturated, and polyunsaturated fatty acids against Echinococcus granulosus fatty-acid-binding protein 1 [version 2; peer review: 1 approved, 2 approved with reservations]

Background The zoonotic infection caused by tapeworms Echinococcus is a neglected tropical disease in poor regions with limited access to suitable sanitary conditions. Hydatid cysts produced by Echinococcus granulosus use fatty-acid-binding proteins (FABP) to obtain the fatty acids and cholesterol n...

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Main Authors: Luis Daniel Goyzueta-Mamani, Berly Cardenas-Pillco, Maria Isabel Herrera Valdivida, Yoan Hidalgo Rosa, Karel Mena-Ulecia, Haruna Luz Barazorda-Ccahuana, Margot Paco-Chipana, Miguel Angel Chavez-Fumagalli
Format: Article
Language:English
Published: F1000 Research Ltd 2024-11-01
Series:F1000Research
Subjects:
Echinococcus granulosus
EgFABP1
fatty acids
gene ontology
quantum mechanics
molecular dynamics simulation
eng
Online Access:https://f1000research.com/articles/13-303/v2
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