The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma

Ovarian carcinoma (OC) has the highest mortality among gynecological carcinomas in developed countries. Many authors have drawn attention to fibrinogen-to-pre-albumin (FPR) and albumin-to-fibrinogen (AFR) ratios and demonstrated that low AFR values and high FPR values correlate with an increased ris...

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Main Authors: Racheva V., Dekova I., Gorcheva Z., Semova T., Dimitrov D., Petkova E.
Format: Article
Language:English
Published: Sciendo 2025-03-01
Series:Acta Medica Bulgarica
Subjects:
Online Access:https://doi.org/10.2478/amb-2025-0006
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author Racheva V.
Dekova I.
Gorcheva Z.
Semova T.
Dimitrov D.
Petkova E.
author_facet Racheva V.
Dekova I.
Gorcheva Z.
Semova T.
Dimitrov D.
Petkova E.
author_sort Racheva V.
collection DOAJ
description Ovarian carcinoma (OC) has the highest mortality among gynecological carcinomas in developed countries. Many authors have drawn attention to fibrinogen-to-pre-albumin (FPR) and albumin-to-fibrinogen (AFR) ratios and demonstrated that low AFR values and high FPR values correlate with an increased risk of mortality and recurrence of carcinoma and may be promising prognostic markers for malignant diseases. As emerging biomarkers, FPR and AFR have significant advantages due to their availability, costeffectiveness, and reliability.
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institution Kabale University
issn 2719-5384
language English
publishDate 2025-03-01
publisher Sciendo
record_format Article
series Acta Medica Bulgarica
spelling doaj-art-f31cac82642a48d6a58a57de4baeb1b42025-08-25T06:11:38ZengSciendoActa Medica Bulgarica2719-53842025-03-01521414710.2478/amb-2025-0006The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian CarcinomaRacheva V.0Dekova I.1Gorcheva Z.2Semova T.3Dimitrov D.4Petkova E.51Clinical Laboratory, University Hospital „Sv. Marina“ Pleven, Medical University – Pleven, Bulgaria2Department of Hepatobiliary and Pancreatic Surgery at the First Clinic of University Hospital „Dr. G. Stranski – Pleven“, Medical University – Pleven, Bulgaria3Clinic of Internal Medicine, University Hospital „Sv. Marina“ Pleven, Medical University – Pleven, Bulgaria4Obstetrics and Gynaecology, University Hospital „Sv. Marina“ Pleven, Medical University – Pleven, Bulgaria4Obstetrics and Gynaecology, University Hospital „Sv. Marina“ Pleven, Medical University – Pleven, Bulgaria5Department of Midwifery care, Faculty of Health Care, Medical University – Pleven, BulgariaOvarian carcinoma (OC) has the highest mortality among gynecological carcinomas in developed countries. Many authors have drawn attention to fibrinogen-to-pre-albumin (FPR) and albumin-to-fibrinogen (AFR) ratios and demonstrated that low AFR values and high FPR values correlate with an increased risk of mortality and recurrence of carcinoma and may be promising prognostic markers for malignant diseases. As emerging biomarkers, FPR and AFR have significant advantages due to their availability, costeffectiveness, and reliability.https://doi.org/10.2478/amb-2025-0006ovarian carcinomaprealbuminalbuminfibrinogenratiosprognosis
spellingShingle Racheva V.
Dekova I.
Gorcheva Z.
Semova T.
Dimitrov D.
Petkova E.
The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
Acta Medica Bulgarica
ovarian carcinoma
prealbumin
albumin
fibrinogen
ratios
prognosis
title The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
title_full The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
title_fullStr The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
title_full_unstemmed The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
title_short The Role of Albumin-To-Fibrinogen and Fibrinogen-To-Prealbumin Ratios in the Development of Ovarian Carcinoma
title_sort role of albumin to fibrinogen and fibrinogen to prealbumin ratios in the development of ovarian carcinoma
topic ovarian carcinoma
prealbumin
albumin
fibrinogen
ratios
prognosis
url https://doi.org/10.2478/amb-2025-0006
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