The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies
Aim of the current study was to clarify the association of carotenoid consumption and chronic obstructive pulmonary disease (COPD) through a meta-analysis of observational studies. We searched the online databases up to August 15, 2024. Both observational studies conducted in human populations were...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464625000271 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823864446945067008 |
|---|---|
| author | Jing Sui Wenbin Shen Yanni Zhang Jiarui Liang Hui Xia Guiju Sun |
| author_facet | Jing Sui Wenbin Shen Yanni Zhang Jiarui Liang Hui Xia Guiju Sun |
| author_sort | Jing Sui |
| collection | DOAJ |
| description | Aim of the current study was to clarify the association of carotenoid consumption and chronic obstructive pulmonary disease (COPD) through a meta-analysis of observational studies. We searched the online databases up to August 15, 2024. Both observational studies conducted in human populations were included, and association between level of carotenoids intake/blood and COPD. We performed a meta-analysis using random-effects models. Seven of 9723 records were included in the present study. The odds ratio (OR) between carotenoids consumption and COPD risk was 0.69 (95 % CI: 0.59–0.80, p < 0.001), which indicates a significant protective effect. In addition, subgroup analysis revealed that the various types of carotenoids including a-carotene, β-carotene and cryptoxanthin were significant in COPD (OR = 0.51, 95 % CI: 0.37–0.69; OR = 0.72, 95 % CI: 0.57–0.92; OR = 0.51, 95 % CI: 0.38–0.69, separately). Conclusion: Carotenoids consumption has a protective effect on the risk of COPD. |
| format | Article |
| id | doaj-art-f3172718316f4132a4521fa0c015c36f |
| institution | Kabale University |
| issn | 1756-4646 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj-art-f3172718316f4132a4521fa0c015c36f2025-02-09T04:59:57ZengElsevierJournal of Functional Foods1756-46462025-02-01125106685The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studiesJing Sui0Wenbin Shen1Yanni Zhang2Jiarui Liang3Hui Xia4Guiju Sun5Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing 210044, China; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, ChinaResearch Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing 210044, ChinaResearch Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing 210044, ChinaResearch Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing 210044, ChinaKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China; Corresponding authors.Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China; Corresponding authors.Aim of the current study was to clarify the association of carotenoid consumption and chronic obstructive pulmonary disease (COPD) through a meta-analysis of observational studies. We searched the online databases up to August 15, 2024. Both observational studies conducted in human populations were included, and association between level of carotenoids intake/blood and COPD. We performed a meta-analysis using random-effects models. Seven of 9723 records were included in the present study. The odds ratio (OR) between carotenoids consumption and COPD risk was 0.69 (95 % CI: 0.59–0.80, p < 0.001), which indicates a significant protective effect. In addition, subgroup analysis revealed that the various types of carotenoids including a-carotene, β-carotene and cryptoxanthin were significant in COPD (OR = 0.51, 95 % CI: 0.37–0.69; OR = 0.72, 95 % CI: 0.57–0.92; OR = 0.51, 95 % CI: 0.38–0.69, separately). Conclusion: Carotenoids consumption has a protective effect on the risk of COPD.http://www.sciencedirect.com/science/article/pii/S1756464625000271Carotenoids consumptionChronic obstructive pulmonary diseaseProtective effectmeta-analysis |
| spellingShingle | Jing Sui Wenbin Shen Yanni Zhang Jiarui Liang Hui Xia Guiju Sun The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies Journal of Functional Foods Carotenoids consumption Chronic obstructive pulmonary disease Protective effect meta-analysis |
| title | The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies |
| title_full | The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies |
| title_fullStr | The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies |
| title_full_unstemmed | The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies |
| title_short | The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies |
| title_sort | protective role of carotenoids in chronic obstructive pulmonary disease a systematic review and meta analysis of observational studies |
| topic | Carotenoids consumption Chronic obstructive pulmonary disease Protective effect meta-analysis |
| url | http://www.sciencedirect.com/science/article/pii/S1756464625000271 |
| work_keys_str_mv | AT jingsui theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT wenbinshen theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT yannizhang theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT jiaruiliang theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT huixia theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT guijusun theprotectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT jingsui protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT wenbinshen protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT yannizhang protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT jiaruiliang protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT huixia protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies AT guijusun protectiveroleofcarotenoidsinchronicobstructivepulmonarydiseaseasystematicreviewandmetaanalysisofobservationalstudies |