Total lesion glycolysis of primary tumor and lymphnodes is a strong predictor for development of distant metastases in oropharyngeal carcinoma patients with independent validation in automatically delineated lesions

Total lesion glycolysis of primary tumor and lymphnodes is a strong predictor for development of distant metastases in oropharyngeal carcinoma patients with independent validation in automatically delineated lesions

Abstract Background Oropharyngeal carcinomas are characterized by an increasing incidence and a relatively good prognosis. Nonetheless, a considerable number of patients develops metachronous distant metastases; identification of these patients is an urgent medical need. Methods This is a retrospect...

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Main Authors: Sebastian Zschaeck, Marina Hajiyianni, Patrick Hausmann, Pavel Nikulin, Emily Kukuk, Christian Furth, Paulina Cegla, Elia Lombardo, Joanna Kazmierska, Adrien Holzgreve, Iosif Strouthos, Carmen Stromberger, Claus Belka, Michael Baumann, Mechthild Krause, Guillaume Landry, Witold Cholewinski, Jorg Kotzerke, Daniel Zips, Jörg van den Hoff, Frank Hofheinz
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Imaging
Subjects:
Head and neck squamous cell carcinoma
Fluorodeoxyglucose positron emission tomography
Oropharynx cancer
Total lesion glycolysis
Online Access:https://doi.org/10.1186/s40644-025-00836-6
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